Recombinant Human NGF
Cat.No. : | NGF-29561TH |
Product Overview : | Recombinant full length Human NGF expressed in modified human 293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this genes expression is associated with allergic rhinitis. |
Biological activity : | The ED50 of NGF-29561TH is typically 0.2-1.0 ng/ml as measured in a cell proliferation assay using the human growth factor dependent TF-1 cell line. |
Form : | Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin |
Storage : | Store at +4°C. |
Sequence Similarities : | Belongs to the NGF-beta family. |
Gene Name : | NGF nerve growth factor (beta polypeptide) [ Homo sapiens ] |
Official Symbol : | NGF |
Synonyms : | NGF; nerve growth factor (beta polypeptide); NGFB; beta-nerve growth factor; |
Gene ID : | 4803 |
mRNA Refseq : | NM_002506 |
Protein Refseq : | NP_002497 |
MIM : | 162030 |
Uniprot ID : | P01138 |
Chromosome Location : | 1p13.1 |
Pathway : | ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Axonal growth stimulation, organism-specific biosystem; |
Function : | growth factor activity; nerve growth factor receptor binding; receptor signaling protein activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
NGF-1508H | Recombinant Human NGF Protein, His (Fc)-Avi-tagged | +Inquiry |
Ngf-10602M | Recombinant Mouse Ngf Protein, His (Fc)-Avi-tagged | +Inquiry |
Ngf-1826R | Recombinant Rat Ngf Protein, His-tagged | +Inquiry |
Ngf-4406M | Active Recombinant Mouse Ngf Protein | +Inquiry |
NGF-257H | Recombinant Active Human NGF Protein, His-tagged(C-ter) | +Inquiry |
◆ Native Protein | ||
Ngf-51M | Native Mouse Nerve Growth Factor 2.5S | +Inquiry |
Ngf-298M | Active Native Mouse Nerve Growth Factor | +Inquiry |
Ngf-182M | Active Native Mouse Ngf Protein | +Inquiry |
◆ Lysates | ||
NGF-001MCL | Recombinant Mouse NGF cell lysate | +Inquiry |
NGF-001HCL | Recombinant Human NGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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