Recombinant Human NQO1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | NQO1-4163H |
Product Overview : | NQO1 MS Standard C13 and N15-labeled recombinant protein (NP_000894) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 30.9 kDa |
AA Sequence : | MVGRRALIVLAHSERTSFNYAMKEA AAAALKKKGWEVVESDLYAMNFNPI ISRKDITGKLKDPANFQYPAESVLA YKEGHLSPDIVAEQKKLEAADLVIF QFPLQWFGVPAILKGWFERVFIGEF AYTYAAMYDKGPFRSKKAVLSITTG GSGSMYSLQGIHGDMNVILWPIQSG ILHFCGFQVLEPQLTYSIGHTPADA RIQILEGWKKRLENIWDETPLYFAP SSLFDLNFQAGFLMKKEVQDEEKNK KFGLSVGHHLGKSIPTDNQIKARKT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | NQO1 NAD(P)H quinone dehydrogenase 1 [ Homo sapiens (human) ] |
Official Symbol : | NQO1 |
Synonyms : | NQO1; NAD(P)H dehydrogenase, quinone 1; DIA4, diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NMOR1; NAD(P)H dehydrogenase [quinone] 1; DHQU; DTD; QR1; azoreductase; diaphorase-4; DT-diaphorase; dioxin-inducible 1; menadione reductase; quinone reductase 1; phylloquinone reductase; NAD(P)H:quinone oxireductase; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); DIA4; NMOR1; NMORI; |
Gene ID : | 1728 |
mRNA Refseq : | NM_000903 |
Protein Refseq : | NP_000894 |
MIM : | 125860 |
UniProt ID : | P15559 |
Products Types
◆ Recombinant Protein | ||
NQO1-1534H | Recombinant Human NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-2909R | Recombinant Rhesus Macaque NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-001H | Active Recombinant Human NQO1 Protein | +Inquiry |
NQO1-6062H | Recombinant Human NQO1 Protein, GST-tagged | +Inquiry |
NQO1-3717R | Recombinant Rat NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NQO1-3725HCL | Recombinant Human NQO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0633 | NQO1 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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