Recombinant Human NR3C2 Protein, GST-tagged
Cat.No. : | NR3C2-6092H |
Product Overview : | Human NR3C2 partial ORF ( NP_000892, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 37.84 kDa |
AA Sequence : | METKGYHSLPEGLDMERRWGQVSQA VERSSLGPTERTDENNYMEIVNVSC VSGAIPNNSTQGSSKEKQELLPCLQ QDNNRPGILTSDIKTELESKELSAT VAESMGLYMD |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NR3C2 nuclear receptor subfamily 3, group C, member 2 [ Homo sapiens ] |
Official Symbol : | NR3C2 |
Synonyms : | NR3C2; nuclear receptor subfamily 3, group C, member 2; MLR; mineralocorticoid receptor; MR; aldosterone receptor; mineralocorticoid receptor 1; mineralocorticoid receptor delta; MCR; NR3C2VIT; FLJ41052; MGC133092; |
Gene ID : | 4306 |
mRNA Refseq : | NM_000901 |
Protein Refseq : | NP_000892 |
MIM : | 600983 |
UniProt ID : | P08235 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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