Recombinant Human NTHL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NTHL1-1982H
• Product Overview: NTHL1 MS Standard C13 and N15-labeled recombinant protein (NP_002519) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.2 kDa
• AA Sequence: MCSPQESGMTALSARMLTRSRSLGP GAGPRGCREEPGPLRRREAAAEARK SHSPVKRPRKAQRLRVAYEGSDSEK GEGAEPLKVPVWEPQDWQQQLVNIR AMRNKKDAPVDHLGTEHCYDSSAPP KVRRYQVLLSLMLSSQTKDQVTAGA MQRLRARGLTVDSILQTDDATLGKL IYPVGFWRSKVKYIKQTSAILQQHY GGDIPASVAELVALPGVGPKMAHLA MAVAWGTVSGIAVDTHVHRIANRLR WTKKATKSPEETRAALEEWLPRELW HEINGLLVGFGQQTCLPVHPRCHAC LNQALCPAAQGLTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NTHL1 nth like DNA glycosylase 1 [ Homo sapiens (human) ]
• Official Symbol: NTHL1
• Synonyms: NTHL1; nth endonuclease III-like 1 (E. coli); nth (E.coli endonuclease III) like 1; endonuclease III-like protein 1; NTH1; OCTS3
• Gene ID: 4913
• mRNA Refseq: NM_002528
• Protein Refseq: NP_002519
• MIM: 602656
• UniProt ID: P78549