Recombinant Human PCSK6 protein, His-tagged

• Cat.No.: PCSK6-3241H
• Product Overview: Recombinant Human PCSK6 protein(Met168~Val487), fused with N-terminal His Tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 44kDa
• Protein Length: Met168~Val487
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: PCSK6 proprotein convertase subtilisin/kexin type 6 [ Homo sapiens ]
• Official Symbol: PCSK6
• Synonyms: PCSK6; proprotein convertase subtilisin/kexin type 6; PACE4, paired basic amino acid cleaving system 4; SPC4; subtilisin like proprotein convertase 4; subtilisin like protease; subtilisin/kexin like protease PACE4; subtilisin/kexin-like protease PACE4; subtilisin-like proprotein convertase 4; paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; PACE4
• Gene ID: 5046
• mRNA Refseq: NM_002570
• Protein Refseq: NP_002561
• MIM: 167405
• UniProt ID: P29122

Reviews

03/20/2019

Outstanding service. High-quality protein analysis.

01/10/2019

Top-notch support. Instrumental in our research achievements.

03/26/2018

Exceptional accuracy. Accelerates our research progress.

Q&As

How does PCSK6 influence the activation of growth factors and hormones?

It activates growth factors and hormones, influencing cell growth and differentiation.

What is the impact of altered PCSK6 activity in diseases like cancer?

Altered PCSK6 activity is associated with cancer progression, impacting cell growth.

What role does PCSK6 play in developmental processes and organogenesis?

PCSK6 is key in development, affecting organ formation and body patterning.

What is the primary function of PCSK6 in protein processing and regulation?

PCSK6 activates precursor proteins into their active forms, essential for protein regulation.

How do genetic variations in PCSK6 affect its enzymatic activity and contribute to developmental disorders?

Mutations in PCSK6 can disrupt protein processing, leading to developmental disorders.

How does PCSK6 interact with other proteases and signaling pathways in the cell?

PCSK6 cooperates with other proteases, playing a role in various cellular pathways.

What potential therapeutic applications could arise from modulating PCSK6 activity in various diseases?

Targeting PCSK6 could be therapeutic in conditions involving abnormal protein activation.