Recombinant Human PDGFRB Protein (33-532aa), C-hIgG-His tagged
Cat.No. : | PDGFRB-129H |
Product Overview : | Recombinant human PDGFRB (33-532aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
Source : | Baculovirus |
Species : | Human |
Tag : | C-hIgG-His |
Form : | Liquid |
Molecular Mass : | 83.3 kDa (739aa) |
Protein Length : | 33-532aa |
AA Sequence : | LVVTPPGPELVLNVSSTFVLTCSGS APVVWERMSQEPPQEMAKAQDGTFS SVLTLTNLTGLDTGEYFCTHNDSRG LETDERKRLYIFVPDPTVGFLPNDA EELFIFLTEITEITIPCRVTDPQLV VTLHEKKGDVALPVPYDHQRGFSGI FEDRSYICKTTIGDREVDSDAYYVY RLQVSSINVSVNAVQTVVRQGENIT LMCIVIGNEVVNFEWTYPRKESGRL VEPVTDFLLDMPYHIRSILHIPSAE LEDSGTYTCNVTESVNDHQDEKAIN ITVVESGYVRLLGEVGTLQFAELHR SRTLQVVFEAYPPPTVLWFKDNRTL GDSSAGEIALSTRNVSETRYVSELT LVRVKVAEAGHYTMRAFHEDAEVQL SFQLQINVPVRVLELSESHPDSGEQ TVRCRGRGMPQPNIIWSACRDLKRC PRELPPTLLGNSSEEESQLETNVTY WEEEQEFEVVSTLRLQHVDRPLSVR CTLRNAVGQDTQEVIVVPHSLPFKV < LEPKSCDKTHTCPPCPAPELLGGPS VFLFPPKPKDTLMISRTPEVTCVVV DVSHEDPEVKFNWYVDGVEVHNAKT KPREEQYNSTYRVVSVLTVLHQDWL NGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSRDELTKNQVS LTCLVKGFYPSDIAVEWESNGQPEN NYKTTPPVLDSDGSFFLYSKLTVDK SRWQQGNVFSCSVMHEALHNHYTQK SLSLSPGKHHHHHH> |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/mL (determined by Bradford assay) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | PDGFRB platelet-derived growth factor receptor, beta polypeptide [ Homo sapiens (human) ] |
Official Symbol : | PDGFRB |
Synonyms : | PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1; |
Gene ID : | 5159 |
mRNA Refseq : | NM_002609 |
Protein Refseq : | NP_002600 |
MIM : | 173410 |
UniProt ID : | P09619 |
Products Types
◆ Recombinant Protein | ||
PDGFRB-416H | Recombinant Human PDGFRB Protein, Fc-tagged | +Inquiry |
PDGFRB-271H | Recombinant Human PDGFRB Protein (ECD) (Glu241Asp), Fc-His-tagged(C-ter) | +Inquiry |
Pdgfrb-189M | Recombinant Mouse Pdgfrb Protein, His-tagged | +Inquiry |
PDGFRB-2573H | Recombinant Human PDGFRB Protein, His-tagged | +Inquiry |
PDGFRB-2058H | Recombinant Human PDGFRB Protein, Fc/His-tagged | +Inquiry |
◆ Lysates | ||
PDGFRB-1107HCL | Recombinant Human PDGFRB cell lysate | +Inquiry |
PDGFRB-1112RCL | Recombinant Rat PDGFRB cell lysate | +Inquiry |
PDGFRB-1046CCL | Recombinant Cynomolgus PDGFRB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1618 | PDGFRb Functional Assay Kit | +Inquiry |
Kit-1617 | U2OS PDGFRb Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket