Recombinant Human Pentraxin 3, His-tagged

• Cat.No.: PTX3-132H
• Product Overview: Recombinant human Pentraxin 3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 44.4 kDa (401aa)

Specification

• Cat. No.: PTX3-132H
• Description: Pentraxin 3(PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. Pentraxin 3 is produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMENS DDYDLMYVNL DNEIDNGLHP TEDPTPCDCG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S
• Purity: > 90% by SDS - PAGE
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT 10% glycerol.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PTX3 pentraxin-related gene, rapidly induced by IL-1 beta [ Homo sapiens ]
• Synonyms: PTX3; TSG-14; TNFAIP5; PTX3; pentraxin-related gene, rapidly induced by IL-1 beta;pentraxin 3; pentraxin-3; pentaxin-related protein PTX3; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
• Gene ID: 5806
• mRNA Refseq: NM_002852
• Protein Refseq: NP_002843
• MIM: 602492
• UniProt ID: P26022
• Chromosome Location: 3q25
• Function: zymosan binding

Reviews

06/23/2022

Using this protein, it was found that its purity was high and there were no obvious impurities.

05/20/2022

PTX3 was observed that its expression level was high, which could meet the experimental requirements.

04/11/2021

Its stability is good, there is no obvious change in the storage and transportation process.

Q&As

How does PTX3 protein work in the immune system?

PTX3 regulates the inflammatory response and immune cell activation by binding to receptors on the surface of inflammatory cells.

What are the interactions of PTX3 protein with other molecules?

PTX3 can perform its function by interacting with other proteins, cytokines, and extracellular matrix molecules.

What are the roles of PTX3 protein in the nervous system?

It has a protective and repairing role in the nervous system and can affect the growth of nerve cells and synapse formation.

What roles does PTX3 protein play in the immune system?

This protein plays a regulatory role in the immune system and can influence the inflammatory response and the activity of immune cells.

Is PTX3 protein involved in any signaling pathways?

Yes, PTX3 can be involved in a variety of signaling pathways that affect cell growth, differentiation, and apoptosis.

How does PTX3 protein regulate cell growth and differentiation?

It can affect signal transduction pathways for cell growth and differentiation by binding to its ligands.