Recombinant Human PLA2G2A

• Cat.No.: PLA2G2A-01H
• Product Overview: Recombinant Human PLA2G2A protein (Met 1 - Cys 144),was expressed in HEK293 Cells.

Specification

• Source: HEK293
• Species: Human
• Form: Lyophilized from sterile 25 mM Tris-HCl, pH7.4, 300 mM NaCl, 1 mM DTT, 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
• Molecular Mass: 15.4 kDa
• Purity: >97% as determined by SDS-PAGE
• Storage: Short Term Storage +4°C. Long Term Storage -20°C. Prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Reconstitution: It is recommended to reconstitute the lyophilized PLA2G2A in 1ml sterile and pre-cooled ddH2O, which can then be further diluted to other aqueous solutions.

Gene Information

• Gene Name: PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) [ Homo sapiens ]
• Official Symbol: PLA2G2A
• Synonyms: PLA2G2A; phospholipase A2, group IIA (platelets, synovial fluid); PLA2B, PLA2L; phospholipase A2, membrane associated; NPS-PLA2; GIIC sPLA2; group IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; non-pancreatic secretory phospholipase A2; MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
• Gene ID: 5320
• mRNA Refseq: NM_000300
• Protein Refseq: NP_000291
• MIM: 172411
• UniProt ID: P14555
• Chromosome Location: 1p35
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem
• Function: calcium ion binding; calcium-dependent phospholipase A2 activity; hydrolase activity; phospholipase A2 activity; phospholipid binding

Reviews

11/23/2022

PLA2G2A's ability to easily attach to the surface of a cell or material.

06/14/2022

It has the characteristics of high safety in clinical treatment.

04/30/2022

The operation is very simple, get started quickly, easy to use, will recommend to others.

Q&As

How to use the expression pattern of PLA2G2A protein for disease diagnosis?

By detecting the expression pattern of PLA2G2A proteins, it can assist in the diagnosis of certain diseases, such as inflammatory diseases, cardiovascular diseases, cancer, etc.

What is the role of PLA2G2A proteins in the immune system?

PLA2G2A proteins have the role of regulating inflammatory response and apoptosis in the immune system, which can affect the survival and function of immune cells.

How to study the regulatory mechanisms of PLA2G2A proteins?

Studying the regulatory mechanism of PLA2G2A proteins requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Is the expression of PLA2G2A protein related to the stage of disease development?

The expression of PLA2G2A protein may be related to the stage of the disease, and the expression level of the PLA2G2A protein may change at different stages of the disease development.

What are the types of mutations in PLA2G2A proteins?

The types of mutations in PLA2G2A proteins include point mutations, insertions/deletions, duplications, etc., which can lead to structural and functional abnormalities of the protein.

What is the relationship of PLA2G2A protein to other genes or proteins?

PLA2G2A proteins have complex relationships with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.