| Description : |
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
175.6 kDa |
| AA Sequence : |
MEVSRRKAPPRPPRPAAPLPLLAYL LALAAPGRGADEPVWRSEQAIGAIA ASQEDGVFVASGSCLDQLDYSLEHS LSRLYRDQAGNCTEPVSLAPPARPR PGSSFSKLLLPYREGAAGLGGLLLT GWTFDRGACEVRPLGNLSRNSLRNG TEVVSCHPQGSTAGVVYRAGRNNRW YLAVAATYVLPEPETASRCNPAASD HDTAIALKDTEGRSLATQELGRLKL CEGAGSLHFVDAFLWNGSIYFPYYP YNYTSGAATGWPSMARIAQSTEVLF QGQASLDCGHGHPDGRRLLLSSSLV EALDVWAGVFSAAAGEGQERRSPTT TALCLFRMSEIQARAKRVSWDFKTA ESHCKEGDQPERVQPIASSTLIHSD LTSVYGTVVMNRTVLFLGTGDGQLL KVILGENLTSNCPEVIYEIKEETPV FYKLVPDPVKNIYIYLTAGKEVRRI RVANCNKHKSCSECLTATDPHCGWC HSLQRCTFQGDCVHSENLENWLDIS SGAKKCPKIQIIRSSKEKTTVTMVG SFSPRHSKCMVKNVDSSRELCQNKS QPNRTCTCSIPTRATYKDVSVVNVM FSFGSWNLSDRFNFTNCSSLKECPA CVETGCAWCKSARRCIHPFTACDPS DYERNQEQCPVAVEKTSGGGRPKEN KGNRTNQALQVFYIKSIEPQKVSTL GKSNVIVTGANFTRASNITMILKGT STCDKDVIQVSHVLNDTHMKFSLPS SRKEMKDVCIQFDGGNCSSVGSLSY IALPHCSLIFPATTWISGGQNITMM GRNFDVIDNLIISHELKGNINVSEY CVATYCGFLAPSLKSSKVRTNVTVK LRVQDTYLDCGTLQYREDPRFTGYR VESEVDTELEVKIQKENDNFNISKK DIEITLFHGENGQLNCSFENITRNQ DLTTILCKIKGIKTASTIANSSKKV RVKLGNLELYVEQESVPSTWYFLIV LPVLLVIVIFAAVGVTRHKSKELSR KQSQQLELLESELRKEIRDGFAELQ MDKLDVVDSFGTVPFLDYKHFALRT FFPESGGFTHIFTEDMHNRDANDKN ESLTALDALICNKSFLVTVIHTLEK QKNFSVKDRCLFASFLTIALQTKLV YLTSILEVLTRDLMEQCSNMQPKLM LRRTESVVEKLLTNWMSVCLSGFLR ETVGEPFYLLVTTLNQKINKGPVDV ITCKALYTLNEDWLLWQVPEFSTVA LNVVFEKIPENESADVCRNISVNVL DCDTIGQAKEKIFQAFLSKNGSPYG LQLNEIGLELQMGTRQKELLDIDSS SVILEDGITKLNTIGHYEISNGSTI KVFKKIANFTSDVEYSDDHCHLILP DSEAFQDVQGKRHRGKHKFKVKEMY LTKLLSTKVAIHSVLEKLFRSIWSL PNSRAPFAIKYFFDFLDAQAENKKI TDPDVVHIWKTNSLPLRFWVNILKN PQFVFDIKKTPHIDGCLSVIAQAFM DAFSLTEQQLGKEAPTNKLLYAKDI PTYKEEVKSYYKAIRDLPPLSSSEM EEFLTQESKKHENEFNEEVALTEIY KYIVKYFDEILNKLERERGLEEAQK QLLHVKVLFDEKKKCKWMTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
