Recombinant Human POC1B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: POC1B-3260H
• Product Overview: POC1B MS Standard C13 and N15-labeled recombinant protein (NP_758440) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.7 kDa
• AA Sequence: MASATEDPVLERYFKGHKAAITSLD LSPNGKQLATASWDTFLMLWNFKPH ARAYRYVGHKDVVTSVQFSPHGNLL ASASRDRTVRLWIPDKRGKFSEFKA HTAPVRSVDFSADGQFLATASEDKS IKVWSMYRQRFLYSLYRHTHWVRCA KFSPDGRLIVSCSEDKTIKIWDTTN KQCVNNFSDSVGFANFVDFNPSGTC IASAGSDQTVKVWDVRVNKLLQHYQ VHSGGVNCISFHPSGNYLITASSDG TLKILDLLEGRLIYTLQGHTGPVFT VSFSKGGELFASGGADTQVLLWRTN FDELHCKGLTKRNLKRLHFDSPPHL LDIYPRTPHPHEEKVETVEINPKLE VIDLQISTPPVMDILSFDSTTTTET SGRTLPDKGEEACGYFLNPSLMSPE CLPTTTKKKTEDMSDLPCESQRSIP LAVTDALEHIMEQLNVLTQTVSILE QRLTLTEDKLKDCLENQQKLFSAVQ QKSTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: POC1B POC1 centriolar protein B [ Homo sapiens (human) ]
• Official Symbol: POC1B
• Synonyms: POC1B; POC1 centriolar protein homolog B (Chlamydomonas); WD repeat domain 51B, WDR51B; POC1 centriolar protein homolog B; FLJ14923; TUWD12; WD repeat-containing protein 51B; PIX1; WDR51B; FLJ41111
• Gene ID: 282809
• mRNA Refseq: NM_172240
• Protein Refseq: NP_758440
• MIM: 614784
• UniProt ID: Q8TC44