Recombinant Human POLK, GST-tagged
Cat.No. : | POLK-765H |
Product Overview : | Human POLK full-length ORF ( AAH50718, 1 a.a. - 472 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass. |
Source : | wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 77.66 kDa |
AA Sequence : | MDSTKEKCDSYKDDLLLRMGLNDNK AGMEGLDKEKINKIIMEATKGSRFY GNELKKEKQVNQRIENMMQQKAQIT SQQLRKAQLQVDRFAMELEQSRNLS NTIVHIDMDAFYAAVEMRDNPELKD KPIAVGSMSMLSTSNYHARRFGVRA AMPGFIAKRLCPQLIIVPPNFDKYR AVSKEVKEILADYDPNFMAMSLDEA YLNITKHLEERQNWPEDKRRYFIKM GSSVENDNPGKEVNKLSEHERSISP LLFEESPSDVQPPGDPFQVNFEEQN NPQILQNSVVFGTSAQEVVKEIRFR IEQKTTLTASAGIAPNTMLAKVCSD KNKPNGQYQILPNRQAVMDFIKDLP IRKVSGIGKVTEKMLKALGIITCTE LYQQRALLSLLFSETSWHYFLHISL GLGSTHLTRDGERKSMSVERTFSEI NKAEEQYSLCQELCSELAQDLQKER LKVLYFDMVSLVFKFFNSKMLP |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot; Antibody Production; Protein Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | POLK polymerase (DNA directed) kappa [ Homo sapiens (human) ] |
Official Symbol : | POLK |
Synonyms : | POLK; DINP; POLQ; DINB1; polymerase (DNA directed) kappa; DNA polymerase kappa; EC 2.7.7.7 |
Gene ID : | 51426 |
mRNA Refseq : | NM_016218 |
Protein Refseq : | NP_057302 |
MIM : | 605650 |
UniProt ID : | Q9UBT6 |
Chromosome Location : | 5q13 |
Pathway : | Fanconi anemia pathway |
Function : | DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding |
Products Types
◆ Recombinant Protein | ||
POLK-763H | Recombinant Human POLK Protein, His-tagged | +Inquiry |
Polk-4991M | Recombinant Mouse Polk Protein, Myc/DDK-tagged | +Inquiry |
POLK-6912M | Recombinant Mouse POLK Protein, His (Fc)-Avi-tagged | +Inquiry |
POLK-1527H | Recombinant Human POLK protein | +Inquiry |
POLK-5757C | Recombinant Chicken POLK | +Inquiry |
◆ Lysates | ||
POLK-3045HCL | Recombinant Human POLK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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