Recombinant Human POLK Protein, His-tagged
Cat.No. : | POLK-763H |
Product Overview : | This Human POLK Protein was over-expressed as a recombinant protein in E. coli with a plasmid carrying a C-terminal histidine-tagged human DNA polymerase (1-560 aa), and highly purified by several steps of chromatography. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 65 kDa |
Purity : | > 90% by SDS-PAGE (CBB staining) |
Applications : | 1) Functional studies on translesion DNA synthesis by DNA polymerase kappa 2) Antigen for western blotting and ELISA by anti-Pol kappa antibody |
Storage : | Sent at 4 centigrade or at -20 centigrade. Upon arrival, centrifuge briefly and store at -20 centigrade or at -80 centigrade for longer storage. |
Concentration : | 3.2 mg/mL as measured by BCA method |
Storage Buffer : | 0.2 M NaCl, 10 mM sodium phosphate buffer (pH 7.0), 50% glycerol |
Gene Name : | POLK |
Official Symbol : | POLK DNA polymerase kappa [ Homo sapiens (human) ] |
Synonyms : | POLK; DNA polymerase kappa; DINP; POLQ; DINB1; DNA polymerase kappa; polymerase (DNA directed) kappa; EC 2.7.7.7 |
Gene ID : | 51426 |
mRNA Refseq : | NM_016218 |
Protein Refseq : | NP_057302 |
MIM : | 605650 |
UniProt ID : | Q9UBT6 |
Products Types
◆ Recombinant Protein | ||
Polk-4991M | Recombinant Mouse Polk Protein, Myc/DDK-tagged | +Inquiry |
POLK-6912M | Recombinant Mouse POLK Protein, His (Fc)-Avi-tagged | +Inquiry |
POLK-765H | Recombinant Human POLK, GST-tagged | +Inquiry |
POLK-837H | Recombinant Human POLK, MYC/DDK-tagged | +Inquiry |
POLK-5757C | Recombinant Chicken POLK | +Inquiry |
◆ Lysates | ||
POLK-3045HCL | Recombinant Human POLK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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