| Description : |
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
119.4 kDa |
| AA Sequence : |
MMPMILTVFLSNNEQILTEVPITPE TTCRDVVEFCKEPGEGSCHLAEVWR GNERPIPFDHMMYEHLQKWGPRREE VKFFLRHEDSPTENSEQGGRQTQEQ RTQRNVINVPGEKRTENGVGNPRVE LTLSELQDMAARQQQQIENQQQMLV AKEQRLHFLKQQERRQQQSISENEK LQKLKERVEAQENKLKKIRAMRGQV DYSKIMNGNLSAEIERFSAMFQEKK QEVQTAILRVDQLSQQLEDLKKGKL NGFQSYNGKLTGPAAVELKRLYQEL QIRNQLNQEQNSKLQQQKELLNKRN MEVAMMDKRISELRERLYGKKIQLN RVNGTSSPQSPLSTSGRVAAVGPYI QVPSAGSFPVLGDPIKPQSLSIASN AAHGRSKSANDGNWPTLKQNSSSSV KPVQVAGADWKDPSVEGSVKQGTVS SQPVPFSALGPTEKPGIEIGKVPPP IPGVGKQLPPSYGTYPSPTPLGPGS TSSLERRKEGSLPRPSAGLPSRQRP TLLPATGSTPQPGSSQQIQQRISVP PSPTYPPAGPPAFPAGDSKPELPLT VAIRPFLADKGSRPQSPRKGPQTVN SSSIYSMYLQQATPPKNYQPAAHSA LNKSVKAVYGKPVLPSGSTSPSPLP FLHGSLSTGTPQPQPPSESTEKEPE QDGPAAPADGSTVESLPRPLSPTKL TPIVHSPLRYQSDADLEALRRKLAN APRPLKKRSSITEPEGPGGPNIQKL LYQRFNTLAGGMEGTPFYQPSPSQD FMGTLADVDNGNTNANGNLEELPPA QPTAPLPAEPAPSSDANDNELPSPE PEELICPQTTHQTAEPAEDNNNNVA TVPTTEQIPSPVAEAPSPGEEQVPP APLPPASHPPATSTNKRTNLKKPNS ERTGHGLRVRFNPLALLLDASLEGE FDLVQRIIYEVEDPSKPNDEGITPL HNAVCAGHHHIVKFLLDFGVNVNAA DSDGWTPLHCAASCNSVHLCKQLVE SGAAIFASTISDIETAADKCEEMEE GYIQCSQFLYGVQEKLGVMNKGVAY ALWDYEAQNSDELSFHEGDALTILR RKDESETEWWWARLGDREGYVPKNL LGLYPRIKPRQRTLASGPTRTRRLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
