Recombinant Human PPP1R8
Cat.No. : | PPP1R8-26964TH |
Product Overview : | Recombinant fragment of Human NIPP1, Isoform Gamma with N-terminal proprietary tag. Predicted MW 36.63kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Ubiquitously expressed, with highest levels in heart and skeletal muscle, followed by brain, placenta, lung, liver and pancreas. Less abundant in kidney. The concentration and ratio between isoforms is cell-type dependent. Isoform Alpha (>90%) and isoform |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | RRMQNFAFSGGLYGGLPPTHSEAGS QPHGIHGTALIGGLPMPYPNLAPDV DLTPVVPSAVNMNPAPNPAVYNPEA VNEPKKKKYAKEAWPGKKPTPSLLI |
Sequence Similarities : | Contains 1 FHA domain. |
Gene Name : | PPP1R8 protein phosphatase 1, regulatory subunit 8 [ Homo sapiens ] |
Official Symbol : | PPP1R8 |
Synonyms : | PPP1R8; protein phosphatase 1, regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; nuclear inhibitor of protein phosphatase 1; activator of RNA decay; ard 1; ARD1; NIPP 1; NIPP1; nuclear subunit of PP 1; PRO2047; protein phospha |
Gene ID : | 5511 |
mRNA Refseq : | NM_002713 |
Protein Refseq : | NP_002704 |
MIM : | 602636 |
Uniprot ID : | Q12972 |
Chromosome Location : | 1p35.3 |
Function : | DNA binding; RNA binding; endonuclease activity; hydrolase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
Ppp1r8-026M | Recombinant Mouse Ppp1r8 Protein, MYC/DDK-tagged | +Inquiry |
PPP1R8-3387R | Recombinant Rhesus Macaque PPP1R8 Protein, His (Fc)-Avi-tagged | +Inquiry |
PPP1R8-2143H | Recombinant Human PPP1R8 Protein (1-209 aa), GST-tagged | +Inquiry |
PPP1R8-3569R | Recombinant Rhesus monkey PPP1R8 Protein, His-tagged | +Inquiry |
PPP1R8-2580C | Recombinant Chicken PPP1R8 | +Inquiry |
◆ Lysates | ||
PPP1R8-2932HCL | Recombinant Human PPP1R8 293 Cell Lysate | +Inquiry |
PPP1R8-2931HCL | Recombinant Human PPP1R8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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