Recombinant Human PPP2R5D Protein, His-tagged

• Cat.No.: PPP2R5D-240H
• Product Overview: Recombinant Human PPP2R5D, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg. Store at -80centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 70 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Publication:
  CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer (2020)

Gene Information

• Gene Name: PPP2R5D protein phosphatase 2, regulatory subunit B, delta [ Homo sapiens ]
• Official Symbol: PPP2R5D
• Synonyms: PPP2R5D; protein phosphatase 2, regulatory subunit B, delta; protein phosphatase 2, regulatory subunit B (B56), delta isoform , protein phosphatase 2, regulatory subunit B, delta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; B56D; PP2A B subunit isoform B-delta; PP2A B subunit isoform R5-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A, B subunit, B delta isoform; PP2A, B subunit, R5 delta isoform; PP2A, B subunit, B56 delta isoform; PP2A, B subunit, PR61 delta isoform; protein phosphatase 2, regulatory subunit B, delta isoform; protein phosphatase 2, regulatory subunit B (B56), delta isoform; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform; MGC2134; MGC8949
• Gene ID: 5528
• mRNA Refseq: NM_006245
• Protein Refseq: NP_006236
• MIM: 601646
• UniProt ID: Q14738