Recombinant Human PTX3, His-tagged

• Cat.No.: PTX3-29169TH
• Product Overview: Recombinant full length human Pentraxin 3 with N terminal His tag; amino acids 18-381 , 44.4kDa.

Specification

• Description: Pentraxin 3(PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMENS DDYDLMYVNL DNEIDNGLHP TEDPTPCDCG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S
• Sequence Similarities: Contains 1 pentaxin domain.

Gene Information

• Gene Name: PTX3 pentraxin 3, long [ Homo sapiens ]
• Official Symbol: PTX3
• Synonyms: PTX3; pentraxin 3, long; pentaxin related gene, rapidly induced by IL 1 beta , pentraxin related gene, rapidly induced by IL 1 beta , TNFAIP5, tumor necrosis factor, alpha induced protein 5; pentraxin-related protein PTX3; TSG 14
• Gene ID: 5806
• mRNA Refseq: NM_002852
• Protein Refseq: NP_002843
• MIM: 602492
• Uniprot ID: P26022
• Chromosome Location: 3q25
• Function: (1->3)-beta-D-glucan binding

Reviews

06/23/2022

Using this protein, it was found that its purity was high and there were no obvious impurities.

05/20/2022

PTX3 was observed that its expression level was high, which could meet the experimental requirements.

04/11/2021

Its stability is good, there is no obvious change in the storage and transportation process.

Q&As

How does PTX3 protein work in the immune system?

PTX3 regulates the inflammatory response and immune cell activation by binding to receptors on the surface of inflammatory cells.

What are the interactions of PTX3 protein with other molecules?

PTX3 can perform its function by interacting with other proteins, cytokines, and extracellular matrix molecules.

What are the roles of PTX3 protein in the nervous system?

It has a protective and repairing role in the nervous system and can affect the growth of nerve cells and synapse formation.

What roles does PTX3 protein play in the immune system?

This protein plays a regulatory role in the immune system and can influence the inflammatory response and the activity of immune cells.

Is PTX3 protein involved in any signaling pathways?

Yes, PTX3 can be involved in a variety of signaling pathways that affect cell growth, differentiation, and apoptosis.

How does PTX3 protein regulate cell growth and differentiation?

It can affect signal transduction pathways for cell growth and differentiation by binding to its ligands.