Recombinant Human RAF1 protein, His&GST-tagged
Cat.No. : | RAF1-413H |
Product Overview : | Recombinant Human RAF1 protein(NP_002871.1)(Ser306-Phe648), fused with His&GST tag, was expressed in Insect Cells. |
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Source : | Insect Cells |
Species : | Human |
Tag : | His&GST |
Form : | Lyophilized from sterile 20 mM Tris, 500 mM Nacl, pH 8.0, 10 % glycerol, 0.5 mM TCEP, 2 mM GSH.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Molecular Mass : | The recombinant human RAF1 consists of 580 amino acids and predicts a molecular mass of 66.9 kDa. |
Protein Length : | Ser306-Phe648 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 70 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 [ Homo sapiens ] |
Official Symbol : | RAF1 |
Synonyms : | RAF1; v-raf-1 murine leukemia viral oncogene homolog 1; RAF proto-oncogene serine/threonine-protein kinase; c Raf; CRAF; Raf 1; Oncogene RAF1; proto-oncogene c-RAF; raf proto-oncogene serine/threonine protein kinase; NS5; Raf-1; c-Raf; |
Gene ID : | 5894 |
mRNA Refseq : | NM_002880 |
Protein Refseq : | NP_002871 |
MIM : | 164760 |
UniProt ID : | P04049 |
Products Types
◆ Recombinant Protein | ||
RAF1-1123H | Recombinant Human RAF1 Protein, GST-tagged | +Inquiry |
RAF1-17H | Recombinant Human RAF1 Protein, N-terminal 6XHis and Avi Tag | +Inquiry |
RAF1-428H | Recombinant Human RAF1 Protein, His-tagged | +Inquiry |
RAF1-442H | Recombinant Human RAF1 Protein, His-tagged | +Inquiry |
RAF1-3964H | Recombinant Human RAF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
RAF1-1463HCL | Recombinant Human RAF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe RAF1 protein is studied through a combination of molecular biology techniques, such as immunohistochemistry, Western blotting, and genetic sequencing, in both clinical and research settings.
RAF1 protein expression is not typically included in routine cancer diagnostics. Instead, mutations and expression levels of other genes, like BRAF, are often analyzed in cancer patients.
Clinical trials involving RAF1 protein are ongoing for conditions like Noonan syndrome and certain cancers. These trials aim to develop new therapies and better understand its role in disease.
RAF1 mutations can affect cardiac development, leading to congenital heart defects and other cardiac issues in patients with Noonan syndrome. This has important clinical implications for cardiologists and genetic counselors.
Yes, RAF1 mutations can be inherited, and they can lead to Noonan syndrome. This can have a significant impact on affected individuals and their families, necessitating specialized medical care and genetic counseling.
Customer Reviews (3)
Write a reviewThey understand that each research project may have unique requirements, and they are more than willing to address these specific needs.
The manufacturer's commitment to providing excellent technical support is truly impressive.
Their prompt and insightful responses to inquiries and troubleshooting requests enable me to tackle experimental obstacles with confidence and efficiency.
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