Recombinant Human RCC1 Protein, Strep-tagged

• Cat.No.: RCC1-181H
• Product Overview: Recombinant Human RCC1 protein, fused with C-terminal Strep tag, was expressed in E. coli.

Specification

• Source: E.coli
• Species: Human
• Tag: Strep
• Form: 25 mM HEPES (pH 7.8), 150 mM NaCl, 10% glycerol, 1 mM TCEP
• Molecular Mass: 46.0 kDa
• Protein length: 2-421
• Storage: Store at -80centigrade. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RCC1 regulator of chromosome condensation 1 [ Homo sapiens ]
• Official Symbol: RCC1
• Synonyms: RCC1; regulator of chromosome condensation 1; CHC1, chromosome condensation 1; regulator of chromosome condensation; cell cycle regulatory protein; SNHG3-RCC1 readthrough transcript; guanine nucleotide-releasing protein; CHC1; RCC1-I; SNHG3-RCC1
• Gene ID: 1104
• mRNA Refseq: NM_001048194
• Protein Refseq: NP_001041659
• MIM: 179710
• UniProt ID: P18754
• Chromosome Location: 1p35.3
• Pathway: Disease, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem; Interactions of Rev with host cellular proteins, organism-specifi
• Function: DNA binding; Ran guanyl-nucleotide exchange factor activity; chromatin binding; guanyl-nucleotide exchange factor activity; histone binding; nucleosomal DNA binding; protein binding

Reviews

09/22/2021

Stability of tRCC1 is highly praised, and its ability to maintain its structural and functional stability even in various extreme environments is truly impressive.

05/02/2020

The green production process of RCC1 focuses on sustainable development and maximizes the utilization of energy and resources by optimizing the production process and equipment.

01/11/2019

This short half-life and high clearance properties of this RCC1 allow its rapid action and rapid clearance in vivo, reducing the risk of side effects.

Q&As

Is RCC1 protein related to the stage and clinicopathological features of lung cancer?

The expression level of RCC1 protein may be related to the stage and clinicopathological features of lung cancer.

How about the regulatory mechanism of RCC1 protein involved in cell mitosis?

RCC1 protein is involved in regulating the progress of cellular mitosis by regulating the formation of new nuclear pores, the decomposition of nuclear membranes, and the separation of chromosomes.

What is the potential of RCC1 protein as a tumor marker?

RCC1 protein has some potential in tumor markers, but more research is needed to verify its clinical application value.

Is RCC1 protein involved in DNA damage repair?

Yes, the RCC1 protein may play an important role in DNA damage repair, helping to maintain genome stability.

What diseases are RCC1 protein mutations associated with?

Mutations in the RCC1 protein are associated with neurological diseases (such as Parkinson's disease) and autoimmune diseases (such as systemic lupus erythematosus).

What is the role of RCC1 protein in immune diseases?

The RCC1 protein may be involved in the initiation and progression of immune diseases by affecting the activity of immune cells and the balance of immune responses.