Recombinant Human RGS14 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | RGS14-3949H |
Product Overview : | RGS14 MS Standard C13 and N15-labeled recombinant protein (NP_006471) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 61.4 kDa |
AA Sequence : | MPGKPKHLGVPNGRMVLAVSDGELS STTGPQGQGEGRGSSLSIHSLPSGP SSPFPTEEQPVASWALSFERLLQDP LGLAYFTEFLKKEFSAENVTFWKAC ERFQQIPASDTQQLAQEARNIYQEF LSSQALSPVNIDRQAWLGEEVLAEP RPDMFRAQQLQIFNLMKFDSYARFV KSPLYRECLLAEAEGRPLREPGSSR LGSPDATRKKPKLKPGKSLPLGVEE LGQLPPVEGPGGRPLRKSFRRELGG TANAALRRESQGSLNSSASLDLGFL AFVSSKSESHRKSLGSTEGESESRP GKYCCVYLPDGTASLALARPGLTIR DMLAGICEKRGLSLPDIKVYLVGNE QALVLDQDCTVLADQEVRLENRITF ELELTALERVVRISAKPTKRLQEAL QPILEKHGLSPLEVVLHRPGEKQPL DLGKLVSSVAAQRLVLDTLPGVKIS KARDKSPCRSQGCPPRTQDKATHPP PASPSSLVKVPSSATGKRQTCDIEG LVELLNRVQSSGAHDQRGLLRKEDL VLPEFLQLPAQGPSSEETPPQTKSA AQPIGGSLNSTTDSALTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RGS14 regulator of G-protein signaling 14 [ Homo sapiens (human) ] |
Official Symbol : | RGS14 |
Synonyms : | RGS14; regulator of G-protein signaling 14; regulator of G protein signalling 14; regulator of G-protein signalling 14; |
Gene ID : | 10636 |
mRNA Refseq : | NM_006480 |
Protein Refseq : | NP_006471 |
MIM : | 602513 |
UniProt ID : | O43566 |
Products Types
◆ Recombinant Protein | ||
RGS14-7564M | Recombinant Mouse RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS14-4674R | Recombinant Rat RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS14-1007H | Recombinant Human RGS14 Protein (P2-L566), Tag Free | +Inquiry |
Rgs14-5493M | Recombinant Mouse Rgs14 Protein, Myc/DDK-tagged | +Inquiry |
RGS14-1008H | Recombinant Human RGS14 Protein (P2-L566), His tagged | +Inquiry |
◆ Lysates | ||
RGS14-1502HCL | Recombinant Human RGS14 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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