Recombinant Human RSPO3 Protein
Cat.No. : | RSPO3-35H |
Product Overview : | Recombinant human R-spondin 3 protein without tag was expressed in E. coli. Animal-free (AOF) and carrier protein-free. Mass spectrometry: single species with expected mass. Analytical reversed-phase: single sharp peak. Recovery from stock vial: >95% |
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Description : | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. |
Source : | E. coli |
Species : | Human |
Molecular Mass : | 17 kDa |
Endotoxin : | <0.005 EU/μg protein (below level of detection) |
Applications : | Intestinal organoid culture |
Storage : | Resuspend in 10mM HCl at >100 μg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade |
Storage Buffer : | Lyophilized from acetonitrile, TFA |
Gene Name : | RSPO3 R-spondin 3 [ Homo sapiens (human) ] |
Official Symbol : | RSPO3 |
Synonyms : | RSPO3; R-spondin 3; PWTSR; THSD2; CRISTIN1; |
Gene ID : | 84870 |
mRNA Refseq : | NM_032784 |
Protein Refseq : | NP_116173 |
MIM : | 610574 |
UniProt ID : | Q9BXY4 |
Products Types
◆ Recombinant Protein | ||
RSPO3-14554M | Active Recombinant Mouse RSPO3 Protein | +Inquiry |
RSPO3-423H | Recombinant Human RSPO3 Protein, His-tagged | +Inquiry |
RSPO3-2315Z | Recombinant Zebrafish RSPO3 | +Inquiry |
RSPO3-2455H | Recombinant Human RSPO3, GST-tagged | +Inquiry |
RSPO3-6636H | Recombinant Human RSPO3 Protein (Gln22-His272), C-His tagged | +Inquiry |
◆ Lysates | ||
RSPO3-1906HCL | Recombinant Human RSPO3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic mutations in RSPO3 can disrupt normal development and tissue regeneration.
Targeting RSPO3 could offer advances in regenerative medicine and cancer therapy by modulating Wnt signaling.
RSPO3 plays a significant role in maintaining stem cell populations and influencing their differentiation.
It stimulates tissue development and regeneration by activating Wnt pathways, essential for cellular proliferation.
RSPO3, a member of the R-spondin family, enhances Wnt signaling, crucial for cellular growth and differentiation.
Altered RSPO3 activity is linked to cancer development and progression, particularly in colorectal cancer.
RSPO3 interacts synergistically with Wnt pathway components, amplifying signal transduction.
Customer Reviews (3)
Write a reviewDependable partner, a vital research collaborator.
Consistency in quality, invaluable for our experiments.
Reliable data source, accelerates our research progress.
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