Recombinant Human RYR1 Protein (1-534 aa), His-tagged
Cat.No. : | RYR1-789H |
Product Overview : | Recombinant Human RYR1 Protein (1-534 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Transport. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal bryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during bryogenesis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 63.3 kDa |
Protein length : | 1-534 aa |
AA Sequence : | MGDAEGEDEVQFLRTDDEVVLQCSA TVLKEQLKLCLAAEGFGNRLCFLEP TSNAQNVPPDLAICCFVLEQSLSVR ALQEMLANTVEAGVESSQGGGHRTL LYGHAILLRHAHSRMYLSCLTTSRS MTDKLAFDVGLQEDATGEACWWTMH PASKQRSEGEKVRVGDDIILVSVSS ERYLHLSTASGELQVDASFMQTLWN MNPICSRCEEGFVTGGHVLRLFHGH MDECLTISPADSDDQRRLVYYEGGA VCTHARSLWRLEPLRISWSGSHLRW GQPLRVRHVTTGQYLALTEDQGLVV VDASKAHTKATSFCFRISKEKLDVA PKRDVEGMGPPEIKYGESLCFVQHV ASGLWLTYAAPDPKALRLGVLKKKA MLHQEGHMDDALSLTRCQQEESQAA RMIHSTNGLYNQFIKSLDSFSGKPR GSGPPAGTALPIEGVILSLQDLIIY FEPPSEDLQHEEKQSKLRSLRNRQS LFQEEGMLSMVLNCIDRLNVYTTAA HFAEFAGEEAAESWKEIVNLLYELL ASLIRGNRS |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | RYR1 ryanodine receptor 1 [ Homo sapiens (human) ] |
Official Symbol : | RYR1 |
Synonyms : | CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; PPP1R137; |
Gene ID : | 6261 |
UniProt ID : | P21817 |
Products Types
◆ Recombinant Protein | ||
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Ryr1-2669M | Recombinant Mouse Ryr1 Protein, His&GST-tagged | +Inquiry |
Ryr1-2038R | Recombinant Rat Ryr1 Protein, His-tagged | +Inquiry |
RYR1-4018H | Recombinant Human RYR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RYR1-790H | Recombinant Human RYR1 protein (Skeletal), His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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