Recombinant Human SCGB3A2 Protein, HIS-tagged

• Cat.No.: SCGB3A2-160H
• Product Overview: Recombinant Human SCGB3A2 fused with His tag at C-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.
• Source: E. coli
• Tag: HIS
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Molecular Mass: 7.9 kDa
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein to the desired concentration in proper buffer.

Gene Information

• Gene Name: SCGB3A2 secretoglobin, family 3A, member 2 [ Homo sapiens ]
• Official Symbol: SCGB3A2
• Synonyms: SCGB3A2; secretoglobin, family 3A, member 2; secretoglobin family 3A member 2; LU103; pneumo secretory protein 1; PNSP1; UGRP1; uteroglobin related protein 1; uteroglobin-related protein 1; pnSP-1
• Gene ID: 117156
• mRNA Refseq: NM_054023
• Protein Refseq: NP_473364
• MIM: 606531
• UniProt ID: Q96PL1

Reviews

12/27/2020

Swift and accurate. Critical for our experiments.

11/09/2019

Integral to our research success. Highly recommended.

03/14/2017

Invaluable service. Boosts research productivity.

Q&As

How does SCGB3A2 contribute to lung development and repair?

It plays a role in lung development and repair, contributing to epithelial cell growth and regeneration.

What role does SCGB3A2 play in pulmonary diseases?

SCGB3A2 is implicated in various pulmonary diseases, including asthma and chronic obstructive pulmonary disease (COPD).

What is the primary role of SCGB3A2 in respiratory function?

SCGB3A2, a secretoglobin, is involved in maintaining respiratory tract lining fluid balance and defending against pathogens.

How does SCGB3A2 interact with other proteins in the lung?

SCGB3A2 works with other lung proteins in cellular signaling and immune responses.

How do genetic variations in SCGB3A2 affect lung health?

Genetic variations in SCGB3A2 can influence susceptibility to respiratory ailments and lung function.

What potential therapeutic applications arise from targeting SCGB3A2 in lung diseases?

Targeting SCGB3A2 could offer new treatment strategies for chronic lung diseases.

What is the impact of altered SCGB3A2 activity on respiratory conditions?

Altered SCGB3A2 activity affects lung defense mechanisms, potentially exacerbating respiratory diseases.