Recombinant Human SLAMF8 Protein, C-His-tagged

• Cat.No.: SLAMF8-120H
• Product Overview: Recombinant Human SLAMF8 Protein with C-His tag was expressed in E. coli.

Specification

• Description: SLAMF8, may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
• Source: E. coli
• Species: Human
• Tag: C-His
• Molecular Mass: ~23 kDa
• AA Sequence: AQVLSKVGGSVLLVAARPPGFQVRE AIWRSLWPSEELLATFFRGSLETLY HSRFLGRAQLHSNLSLELGPLESGD SGNFSVLMVDTRGQPWTQTLQLKVY DAVPRPVVQVFIAVERDAQPSKTCQ VFLSCWAPNISEITYSWRRETTMDF GMEPHSLFTDGQVLSISLGPGDRDV AYSCIVSNPVSWDLATVTPWDSCHH EAAPGKASYKD
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Concentration: ≥0.5 mg/mL
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: SLAMF8 SLAM family member 8 [ Homo sapiens (human) ]
• Official Symbol: SLAMF8
• Synonyms: SLAMF8; SLAM family member 8; BLAME; CD353; SBBI42; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; FLJ20442; MGC129578
• Gene ID: 56833
• mRNA Refseq: NM_020125
• Protein Refseq: NP_064510
• MIM: 606620
• UniProt ID: Q9P0V8

Reviews

10/19/2021

Perfect for biological assays.

03/03/2021

Product works as expected.

06/20/2020

Very reliable, worth the price.

Q&As

How is SLAMF8 implicated in inflammatory and autoimmune conditions?

Dysregulation of SLAMF8 can contribute to inflammatory and autoimmune diseases.

Are there potential therapeutic interventions targeting SLAMF8?

Therapeutic interventions could potentially target SLAMF8 to modulate immune responses in various diseases.

What role does SLAMF8 play in the regulation of immune responses?

It acts as an inhibitory receptor, modulating immune cell activation and cytokine production.

What are the molecular mechanisms governing SLAMF8 activity?

SLAMF8 activity is governed by interactions with other cell surface receptors and intracellular signaling pathways.

In which immune cells is SLAMF8 predominantly expressed?

SLAMF8 is predominantly found in myeloid cells, like macrophages and dendritic cells.

What is the primary function of SLAMF8 in the immune system?

SLAMF8 regulates immune responses, particularly in myeloid cells.

How does SLAMF8 contribute to immune cell signaling?

It participates in cell-cell signaling, influencing immune cell activation and function.