Recombinant Human SOD3

• Cat.No.: SOD3-1038H

Specification

• Cat. No.: SOD3-1038H
• Description: Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
• Source: E. coli
• Species: Human
• Storage: Superoxide dismutase 4 is supplied with a vial of storage buffer (20mM Tris, pH7.5/1mM EDTA). Store at -80°C.
• Pathways: Folate Metabolism; Oxidative Stress; Selenium Pathway

Gene Information

• Gene Name: SOD3 superoxide dismutase 3, extracellular [ Homo sapiens ]
• Official Symbol: SOD3
• Synonyms: SOD3; superoxide dismutase 3, extracellular; EC-SOD; MGC20077; extracellular superoxide dismutase [Cu-Zn]; OTTHUMP00000158715; EC 1.15.1.1; Extracellular superoxide dismutase [Cu-Zn]
• Gene ID: 6649
• mRNA Refseq: NM_003102
• Protein Refseq: NP_003093
• MIM: 185490
• UniProt ID: P08294
• Chromosome Location: 4pter-q21
• Function: copper ion binding; heparin binding; metal ion binding; oxidoreductase activity; protein binding; superoxide dismutase activity; zinc ion binding

Reviews

02/19/2023

Trusted for results accuracy. A research necessity.

06/22/2017

Efficient and dependable. Accelerates our research progress.

06/12/2017

Enhances research credibility. Consistent and trustworthy.

Q&As

What potential therapeutic applications arise from targeting SOD3 in oxidative stress-related conditions?

Enhancing SOD3 activity could be a therapeutic strategy in treating oxidative stress-related diseases.

How do genetic variations in SOD3 affect its antioxidant function?

Genetic mutations in SOD3 can impair its ability to scavenge free radicals, affecting its protective role.

How does SOD3 contribute to cellular protection against free radicals?

It protects cells from oxidative damage by converting free radicals to less harmful substances.

What is the impact of altered SOD3 activity on aging and age-related diseases?

Altered SOD3 activity is linked with accelerated aging and the development of age-related diseases.

How does SOD3 interact with other cellular antioxidants?

SOD3 works alongside other antioxidants, contributing to the overall oxidative defense system.

What is the primary role of SOD3 in oxidative stress management?

SOD3, a type of superoxide dismutase, is crucial for neutralizing superoxide radicals, reducing oxidative stress.

What role does SOD3 play in cardiovascular health?

SOD3 is important for cardiovascular health, preventing oxidative damage in blood vessels.