Recombinant Human SOD3 Protein, His-tagged
Cat.No. : | SOD3-1235H |
Product Overview : | Recombinant Human SOD3 Protein (Trp19-Ala240) with His tag was expressed in CHO. |
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Description : | This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. |
Source : | CHO |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 25.8 kDa; Accurate Molecular Mass: 30 kDa |
Protein length : | Trp19-Ala240 |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | SOD3 superoxide dismutase 3, extracellular [ Homo sapiens (human) ] |
Official Symbol : | SOD3 |
Synonyms : | SOD3; superoxide dismutase 3, extracellular; extracellular superoxide dismutase [Cu-Zn]; EC SOD; EC-SOD; MGC20077; |
Gene ID : | 6649 |
mRNA Refseq : | NM_003102 |
Protein Refseq : | NP_003093 |
MIM : | 185490 |
UniProt ID : | P08294 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionEnhancing SOD3 activity could be a therapeutic strategy in treating oxidative stress-related diseases.
Genetic mutations in SOD3 can impair its ability to scavenge free radicals, affecting its protective role.
It protects cells from oxidative damage by converting free radicals to less harmful substances.
Altered SOD3 activity is linked with accelerated aging and the development of age-related diseases.
SOD3 works alongside other antioxidants, contributing to the overall oxidative defense system.
SOD3, a type of superoxide dismutase, is crucial for neutralizing superoxide radicals, reducing oxidative stress.
SOD3 is important for cardiovascular health, preventing oxidative damage in blood vessels.
Customer Reviews (3)
Write a reviewTrusted for results accuracy. A research necessity.
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