Recombinant Human STAMBP Protein (Lys126-Ser368), His tagged
Cat.No. : | STAMBP-5564H |
Product Overview : | Recombinant human STAMBP (Lys126-Ser368) fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 27.73 kDa |
Protein Length : | Lys126-Ser368 |
Purity : | > 90 % as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | STAMBP STAM binding protein [ Homo sapiens (human) ] |
Official Symbol : | STAMBP |
Synonyms : | STAMBP; STAM binding protein; STAM-binding protein; AMSH; endosome-associated ubiquitin isopeptidase; associated molecule with the SH3 domain of STAM; MGC126516; MGC126518; |
Gene ID : | 10617 |
mRNA Refseq : | NM_006463 |
Protein Refseq : | NP_006454 |
MIM : | 606247 |
UniProt ID : | O95630 |
Products Types
◆ Recombinant Protein | ||
STAMBP-11H | Active Recombinant Human STAMBP Protein (Full Length), N-His-tagged | +Inquiry |
STAMBP-4323R | Recombinant Rhesus Macaque STAMBP Protein, His (Fc)-Avi-tagged | +Inquiry |
STAMBP-0340H | Recombinant Human STAMBP Protein (S2-R424), His tagged | +Inquiry |
STAMBP-5435R | Recombinant Rat STAMBP Protein, His (Fc)-Avi-tagged | +Inquiry |
STAMBP-1350S | Recombinant Human STAMBP Protein (S2-R424), Tag Free | +Inquiry |
◆ Lysates | ||
STAMBP-1427HCL | Recombinant Human STAMBP 293 Cell Lysate | +Inquiry |
STAMBP-1428HCL | Recombinant Human STAMBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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