Recombinant Human TAT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TAT-5256H
• Product Overview: TAT MS Standard C13 and N15-labeled recombinant protein (NP_000344) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.4 kDa
• AA Sequence: MDPYMIQMSSKGNLSSILDVHVNVG GRSSVPGKMKGRKARWSVRPSDMAK KTFNPIRAIVDNMKVKPNPNKTMIS LSIGDPTVFGNLPTDPEVTQAMKDA LDSGKYNGYAPSIGFLSSREEIASY YHCPEAPLEAKDVILTSGCSQAIDL CLAVLANPGQNILVPRPGFSLYKTL AESMGIEVKLYNLLPEKSWEIDLKQ LEYLIDEKTACLIVNNPSNPCGSVF SKRHLQKILAVAARQCVPILADEIY GDMVFSDCKYEPLATLSTDVPILSC GGLAKRWLVPGWRLGWILIHDRRDI FGNEIRDGLVKLSQRILGPCTIVQG ALKSILCRTPGEFYHNTLSFLKSNA DLCYGALAAIPGLRPVRPSGAMYLM VGIEMEHFPEFENDVEFTERLVAEQ SVHCLPATCFEYPNFIRVVITVPEV MMLEACSRIQEFCEQHYHCAEGSQE ECDKTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TAT tyrosine aminotransferase [ Homo sapiens (human) ]
• Official Symbol: TAT
• Synonyms: TAT; tyrosine aminotransferase; tyrosine aminotransferase, cytosolic; L-tyrosine:2-oxoglutarate aminotransferase
• Gene ID: 6898
• mRNA Refseq: NM_000353
• Protein Refseq: NP_000344
• MIM: 613018
• UniProt ID: P17735