Recombinant Human TNFRSF10B Protein, Fc-tagged
Cat.No. : | TNFRSF10B-463H |
Product Overview : | Recombinant human TNFRSF10B protein with Fc tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | 40.5 kDa |
Protein Length : | 440 |
AA Sequence : | MEQRGQNAPAASGARKRHGPGPREA RGARPGPRVPKTLVLVVAAVLLLVS AESALITQQDLAPQQRAAPQQKRSS PSEGLCPPGHHISEDGRDCISCKYG QDYSTHWNDLLFCLRCTRCDSGEVE LSPCTTTRNTVCQCEEGTFREEDSP EMCRKCRTGCPRGMVKVGDCTPWSD IECVHKESGTKHSGEVPAVEETVTS SPGTPASPCSLSGIIIGVTVAAVVL IVAVFVCKSLLWKKVLPYLKGICSG GGGDPERVDRSSQRPGAEDNVLNEI VSILQPTQVPEQEMEVQEPAEPTGV NMLSPGESEHLLEPAEAERSQRRRL LVPANEGDPTETLRQCFDDFADLVP FDSWEPLMRKLGLMDNEIKVAKAEA AGHRDTLYTMLIKWVNKTGRDASVH TLLDALETLGERLAKQKIEDHLLSS GKFMYLEGNADSAMS |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name : | TNFRSF10B tumor necrosis factor receptor superfamily, member 10b [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF10B |
Synonyms : | TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor superfamily member 10B; CD262; DR5; KILLER; TRAIL R2; TRICK2A; TRICKB; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer); TRICK2; ZTNFR9; TRAILR2; TRICK2B; TRAIL-R2; KILLER/DR5; |
Gene ID : | 8795 |
mRNA Refseq : | NM_003842 |
Protein Refseq : | NP_003833 |
MIM : | 603612 |
UniProt ID : | O14763 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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