Recombinant Human TRIM33 Protein, Flag-tagged
Cat.No. : | TRIM33-336H |
Product Overview : | Full length Recombinant Human TRIM33 (Tripartite Motif Containing 33) Protein is produced in SF9 Insect Cells and is fused with a Flag tag at the N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | TRIM33 (UniProt/Swiss-Prot entry Q9UPN9) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. TRIM33 is an E3 ubiquitin-protein ligase, which promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. It may act as a transcriptional corepressor and inhibits the transcriptional response to the TGF-beta/BMP signaling cascade. However, molecules that interact with this protein have not yet been identified..TRIM33 also plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Defects in TRIM24 cause thyroid papillary carcinoma. |
Source : | Insect Cells |
Species : | Human |
Tag : | Flag |
Form : | 20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT. |
Purity : | Purified using FPLC, >95% purity as determined by SDS-PAGE. |
Notes : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Stability : | Guaranteed stable for 2 years from date of receipt when stored properly. |
Storage : | Store at -80 centigrade. |
Concentration : | 0.5 µg/µl |
Gene Name : | TRIM33 tripartite motif containing 33 [ Homo sapiens ] |
Official Symbol : | TRIM33 |
Synonyms : | TRIM33; tripartite motif containing 33; FLJ11429; KIAA1113; PTC7; ret fused gene 7; RFG7; TF1G; TIF1G; TIF1GAMMA; TIFGAMMA; ECTO; FLJ32925; |
Gene ID : | 51592 |
mRNA Refseq : | NM_015906 |
Protein Refseq : | NP_056990 |
MIM : | 605769 |
UniProt ID : | Q9UPN9 |
Products Types
◆ Recombinant Protein | ||
Trim33-6654M | Recombinant Mouse Trim33 Protein, Myc/DDK-tagged | +Inquiry |
TRIM33-2258H | Recombinant Human TRIM33 Protein, His (Fc)-Avi-tagged | +Inquiry |
TRIM33-506H | Recombinant Human TRIM33 Protein, DDK-tagged | +Inquiry |
TRIM33-229H | Recombinant Human TRIM33 Protein, GST-tagged | +Inquiry |
TRIM33-228H | Recombinant Human TRIM33 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TRIM33-781HCL | Recombinant Human TRIM33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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