Recombinant Mouse Trim33 Protein, Myc/DDK-tagged
Cat.No. : | Trim33-6654M |
Product Overview : | Purified recombinant protein of mouse full-length tripartite motif-containing 33 (Trim33), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade). |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 124.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Trim33 tripartite motif-containing 33 [ Mus musculus (house mouse) ] |
Official Symbol : | Trim33 |
Synonyms : | TRIM33; tripartite motif-containing 33; E3 ubiquitin-protein ligase TRIM33; TIF1-gamma; ectodermin homolog; tripartite motif protein 33; tripartite motif-containing protein 33; transcription intermediary factor 1-gamma; Ecto; Tif1g; AI413936; mKIAA1113; ectodermin; 8030451N04Rik; DKFZp586K1123 |
Gene ID : | 94093 |
mRNA Refseq : | NM_053170 |
Protein Refseq : | NP_444400 |
UniProt ID : | Q99PP7 |
Products Types
◆ Recombinant Protein | ||
TRIM33-336H | Recombinant Human TRIM33 Protein, Flag-tagged | +Inquiry |
TRIM33-2258H | Recombinant Human TRIM33 Protein, His (Fc)-Avi-tagged | +Inquiry |
TRIM33-227H | Recombinant Human TRIM33 Protein, GST-tagged | +Inquiry |
TRIM33-228H | Recombinant Human TRIM33 Protein, His-tagged | +Inquiry |
TRIM33-230H | Recombinant Human TRIM33 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TRIM33-781HCL | Recombinant Human TRIM33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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