Recombinant Human Zeta-chain (TCR) Associated Protein Kinase 70kDa
Cat.No. : | ZAP70-98H |
Product Overview : | Recombinant Human Zeta Chain Associated Protein Kinase 70 protein expressed inE.coliencodes C-terminal 130 amino acids and has a molecular mass of 40 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ZAP70-98H |
Description : | Mutations in ZAP-70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP-70 expression also defines a subset of Chronic Lymphocytic Leukaemia (CLL) in patients with unmutated Ig gene and poor clinical course. |
Source : | Recombinant Human ZAP70 protein encoding C-terminal 130 amino acids expressed inE.coli. |
Formulation : | Recombinant Human ZAP70 C-terminal protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
Application And Suggested Dilutions : | •ELISA •Inhibition Assays •Western Blotting. |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 40 kDa. |
Storage & Stability : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. |
Gene Name : | ZAP70 zeta-chain (TCR) associated protein kinase 70kDa [ Homo sapiens ] |
Synonyms : | ZAP70; zeta-chain (TCR) associated protein kinase 70kDa; SRK; STD; TZK; ZAP-70; FLJ17670; FLJ17679; zeta-chain (TCR) associated protein kinase (70 kD); Tyrosine-protein kinase ZAP-70;70 kDa zeta-associated protein Syk-related tyrosine kinase; EC 2.7.10.2; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD |
Gene ID : | 7535 |
mRNA Refseq : | NM_001079 |
Protein Refseq : | NP_001070 |
MIM : | 176947 |
UniProt ID : | P43403 |
Chromosome Location : | 2q12 |
Pathway : | Natural killer cell mediated cytotoxicity; Primary immunodeficiency; T cell receptor signaling pathway; Signaling in Immune system |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; phosphotyrosine binding; transferase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
ZAP70-2382H | Recombinant Human ZAP70 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZAP70-1511H | Active Recombinant Human ZAP70 Protein, GST-tagged | +Inquiry |
ZAP70-10274M | Recombinant Mouse ZAP70 Protein, His (Fc)-Avi-tagged | +Inquiry |
Zap70-7046M | Recombinant Mouse Zap70 Protein, Myc/DDK-tagged | +Inquiry |
ZAP70-458H | Recombinant Human ZAP70, GST-tagged, Active | +Inquiry |
◆ Lysates | ||
ZAP70-1948HCL | Recombinant Human ZAP70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket