Recombinant Mouse Acadm Protein, MYC/DDK-tagged
Cat.No. : | Acadm-503M |
Product Overview : | Purified recombinant protein of full-length mouse acyl-Coenzyme A dehydrogenase, medium chain (Acadm), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C6- and C12-acylCoA. In mice, deficiency of this gene can cause neonatal mortality as well as fasting and cold intolerance. This gene has multiple, intronless pseudogenes. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 46.4 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Acadm acyl-Coenzyme A dehydrogenase, medium chain [ Mus musculus (house mouse) ] |
Official Symbol : | Acadm |
Synonyms : | Acadm; acyl-Coenzyme A dehydrogenase, medium chain; MCAD; AU018656; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; EC 1.3.8.7 |
Gene ID : | 11364 |
mRNA Refseq : | NM_007382 |
Protein Refseq : | NP_031408 |
UniProt ID : | P45952 |
Products Types
◆ Recombinant Protein | ||
ACADM-23H | Recombinant Human ACADM Protein, His-tagged | +Inquiry |
ACADM-238M | Recombinant Mouse ACADM Protein, His (Fc)-Avi-tagged | +Inquiry |
ACADM-12251Z | Recombinant Zebrafish ACADM | +Inquiry |
ACADM-134H | Recombinant Human ACADM Protein, GST-Tagged | +Inquiry |
ACADM-0657H | Recombinant Human ACADM Protein (Lys26-Asn421), N-His-tagged | +Inquiry |
◆ Lysates | ||
ACADM-9114HCL | Recombinant Human ACADM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe activity of acyl-CoA dehydrogenase medium chain contributes to the breakdown of medium-chain fatty acids to produce energy in cells.
There are currently no known inhibitors or activators of acyl-CoA dehydrogenase medium chain protein.
Research is ongoing to further understand the function and regulation of acyl-CoA dehydrogenase medium chain protein, as well as its role in metabolic disorders.
Mutations in this protein are associated with a variety of metabolic disorders, including medium-chain acyl-CoA dehydrogenase deficiency.
The expression of acyl-CoA dehydrogenase medium chain is regulated by a variety of factors, including gene expression and protein degradation pathways.
Acyl-CoA dehydrogenase medium chain protein is located in the mitochondrial matrix.
Acyl-CoA dehydrogenase medium chain protein has specificity for medium-chain fatty acyl-CoA substrates.
Acyl-CoA dehydrogenase medium chain protein has a flavin adenine dinucleotide (FAD)-binding domain that is essential for its function.
Acyl-CoA dehydrogenase medium chain protein catalyzes the first step in the 尾-oxidation of medium-chain fatty acids.
Acyl-CoA dehydrogenase medium chain plays a key role in energy metabolism and fatty acid oxidation in cells.
Customer Reviews (2)
Write a reviewDemonstrates excellent stability and consistency in long-term storage.
Highly effective in detecting post-translational modifications of the target protein.
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