Recombinant Mouse ACOT10 Protein

• Cat.No.: ACOT10-1196M
• Product Overview: Recombinant Mouse ACOT10 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Acot10 acyl-CoA thioesterase 10 [ Mus musculus ]
• Official Symbol: ACOT10
• Gene ID: 64833
• mRNA Refseq: NM_022816.2
• Protein Refseq: NP_073727.2
• UniProt ID: Q32MW3

Q&As

Are there any natural compounds that can modulate ACOT10 activity?

Yes, several natural compounds have been identified that can modulate ACOT10 activity, including resveratrol, curcumin, and quercetin. These compounds have been shown to improve metabolic health and may have therapeutic potential for metabolic disorders.

How does ACOT10 impact mitochondrial function?

ACOT10 has been shown to impact mitochondrial function by regulating the production of reactive oxygen species (ROS) and the utilization of fatty acids for energy production. In particular, studies have suggested that ACOT10 may regulate the balance between fatty acid oxidation and the production of ROS, which is important for mitochondrial health and function.

Can ACOT10 be used as a therapeutic target for metabolic disorders?

Yes, ACOT10 is a potential therapeutic target for metabolic disorders such as diabetes and obesity. By modulating the activity or expression of ACOT10, it may be possible to regulate lipid metabolism and improve metabolic health.

Are there any drugs currently available that target ACOT10?

As of yet, there are no drugs that specifically target ACOT10. However, the protein is a promising target for drug discovery, and researchers are actively searching for compounds that can modulate its activity.

How is ACOT10 regulated within the body?

ACOT10 is regulated at the transcriptional and post-transcriptional levels. The expression of the ACOT10 gene is regulated by transcription factors, such as PPARs and LXR, that respond to changes in nutrient availability and metabolic status. Additionally, the activity of ACOT10 can be modified by post-translational modifications, such as phosphorylation and acetylation.

How does ACOT10 affect lipid metabolism?

ACOT10 is an acyl-CoA thioesterase that plays a role in the metabolism of fatty acids. It catalyzes the hydrolysis of acyl-CoA esters, which are important intermediates in lipid metabolism. By regulating the breakdown of these compounds, ACOT10 can impact the storage and oxidation of fatty acids within cells.

Are there any known side effects of targeting ACOT10 for drug development?

However, it is important to note that any drug development process involves rigorous testing to ensure safety and efficacy before it can be prescribed to patients.

Can ACOT10 be used for weight loss?

While ACOT10 may play a role in lipid metabolism, there is currently no evidence to suggest that it can be used for weight loss. However, it may have potential applications in the development of drugs to treat obesity.

Is there potential for using ACOT10 in sports nutrition or performance enhancement?

Can ACOT10 be used as a biomarker for metabolic disorders?

There is some evidence to suggest that ACOT10 may be a useful biomarker for certain metabolic disorders. For example, studies have shown that levels of ACOT10 are decreased in patients with type 2 diabetes. However, more research is needed to determine the utility of ACOT10 as a biomarker for other metabolic disorders.

Can ACOT10 play a role in cancer development?

While ACOT10 may play a role in energy metabolism and lipid utilization, its potential for use in sports nutrition or performance enhancement is not well-established. Further research is needed to understand how ACOT10 could impact athletic performance and whether it could be used as a nutritional or therapeutic intervention for athletes.

Is ACOT10 specific to humans, or is it also found in other organisms?

ACOT10 is found in many different organisms, including mammals, birds, and fish. However, the specific functions of the protein may vary between species.

Is there any potential for using ACOT10 as a diagnostic tool for metabolic disorders?

While more research is needed, ACOT10 may have potential as a diagnostic tool for metabolic disorders. Studies have shown that decreased levels of ACOT10 are associated with type 2 diabetes, and further research may identify other correlations between ACOT10 and metabolic health.

How can ACOT10 be used to treat diabetes?

ACOT10 is involved in the regulation of insulin sensitivity and glucose metabolism. By targeting this protein, researchers may be able to develop drugs that improve insulin sensitivity and glucose homeostasis in patients with diabetes.