Recombinant Mouse ACSF3 Protein Pre-coupled Magnetic Beads

• Cat.No.: ACSF3-271M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Acsf3 acyl-CoA synthetase family member 3 [ Mus musculus ]
• Official Symbol: ACSF3
• Gene ID: 257633
• mRNA Refseq: NM_144932.3
• Protein Refseq: NP_659181.2
• UniProt ID: Q3URE1

Reviews

11/05/2022

This is my go-to supplier for recombinant proteins. Always reliable and consistent.

09/10/2021

The purity of the recombinant protein was exceptional. Very impressed.

01/20/2019

Highly recommend this company for all your recombinant protein needs.

05/05/2018

Quick and easy ordering process. Received my recombinant protein in a timely manner.

01/19/2018

The recombinant protein arrived on time and in perfect condition. No issues at all.

Q&As

What is the relationship between ACSF3 and obesity?

Several studies have found a correlation between ACSF3 gene expression and obesity, with higher ACSF3 expression levels observed in obese individuals.

What is the biochemical function of ACSF3 in phospholipid synthesis?

ACSF3 catalyzes the activation of fatty acids for use in phospholipid synthesis, a crucial component of membrane structure and function.

What is the role of ACSF3 in the production of the neurotransmitter acetylcholine?

ACSF3 is involved in the production of acetyl-CoA, which is a substrate for the enzyme choline acetyltransferase (ChAT) that catalyzes the formation of acetylcholine from choline and acetyl-CoA. Therefore, ACSF3 indirectly contributes to the production of acetylcholine, which is an important neurotransmitter in the nervous system.

What is the mechanism of ACSF3 in fatty acid activation?

ACSF3 catalyzes the activation of long-chain fatty acids by transferring the fatty acid to CoA, forming acyl-CoA, which can be used in various metabolic processes.

How does ACSF3 enzyme interact with other proteins?

ACSF3 interacts with several proteins, including fatty acid transport proteins, diacylglycerol acyltransferases, and peroxisome proliferator-activated receptors.

What are the implications of ACSF3 dysregulation?

Dysregulation of ACSF3 gene expression has been linked to several metabolic disorders, including obesity, insulin resistance, and type 2 diabetes.

What is the role of ACSF3 in the metabolism of branched-chain fatty acids?

ACSF3 has been shown to activate branched-chain fatty acids, such as phytanic acid and pristanic acid, which are derived from dietary sources or produced by gut microbiota. ACSF3 activates these fatty acids by converting them into their respective CoA esters, which can then be further metabolized in the peroxisomes.

How is ACSF3 gene expression regulated?

ACSF3 gene expression is regulated by various factors, including hormones, transcription factors, and epigenetic modifications.

How is ACSF3 expression regulated in cells?

The expression of ACSF3 can be regulated at both the transcriptional and post-transcriptional levels. Transcriptional regulation can be mediated by factors such as peroxisome proliferator-activated receptor (PPAR) and sterol regulatory element-binding protein (SREBP), which can activate or repress the transcription of the ACSF3 gene. Post-transcriptional regulation can occur through mechanisms such as alternative splicing, microRNA-mediated degradation, and protein degradation via the ubiquitin-proteasome system.

What is the subcellular localization of ACSF3?

ACSF3 is primarily localized in the mitochondria of cells, specifically in the mitochondrial outer membrane, where it functions in the beta-oxidation of fatty acids.