Recombinant Mouse ALOX12E Protein
Cat.No. : | ALOX12E-1565M |
Product Overview : | Recombinant Mouse ALOX12E full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
- Download
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Alox12e arachidonate lipoxygenase, epidermal [ Mus musculus ] |
Official Symbol : | ALOX12E |
Gene ID : | 11685 |
mRNA Refseq : | NM_145684.1 |
Protein Refseq : | NP_663717.1 |
MIM : | |
UniProt ID : | P55249 |
Products Types
◆ Recombinant Protein | ||
ALOX12E-482M | Recombinant Mouse ALOX12E Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX12E-291R | Recombinant Rat ALOX12E Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX12E-635R | Recombinant Rat ALOX12E Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (15)
Ask a questionThe detection methods of ALOX12E include immunohistochemistry, real-time fluorescence quantitative PCR, etc.
ALOX12E may be involved in the regulation of the effects of estrogen on the skin, but the specific role needs to be studied.
ALOX12E catalyzes the oxidation of arachidonic acid in epidermal cells to form 12-hydroxyarachidonic acid, thus participating in the keratinization process and skin barrier formation.
Overexpression of ALOX12E is associated with psoriasis, atopic dermatitis, and lupus erythematosus.
This protein may be involved in the regulation of skin immune response, but its specific role needs further study.
The gene for ALOX12E is located on human chromosome 17.
Point mutations in ALOX12E can lead to skin disorders such as abnormal keratosis and ichthyosis.
It may be activated in response to cell stimulation, such as trauma.
Inhibitors of ALOX12E include arabidopsis, procainamide, etc.
The ALOX12E signaling pathway is mainly realized through the MAPK signaling pathway.
ALOX12E may play an anti-apoptotic role in cell apoptosis.
ALOX12E has been linked to skin cancer, and its inhibitors can be used to treat skin cancer.
Abnormalities in ALOX12E have been linked to conditions such as psoriasis, atopic dermatitis and dry skin.
ALOX12E is mainly expressed in the skin and cornea.
The expression of ALOX12E is affected by many factors such as extracellular calcium ion concentration, extracellular oxygen partial pressure, and cytokines.
Customer Reviews (3)
Write a reviewWhen desensitize specific allergens, ALOX12E has a strong potential.
ALOX12E showed good compatibility and stability with various excipients.
The pharmacodynamic parameters of ALOX12E were better.
Ask a Question for All ALOX12E Products
Required fields are marked with *
My Review for All ALOX12E Products
Required fields are marked with *
Inquiry Basket