Recombinant Mouse ALPK2 Protein
Cat.No. : | ALPK2-1573M |
Product Overview : | Recombinant Mouse ALPK2 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Alpk2 alpha-kinase 2 [ Mus musculus ] |
Official Symbol : | ALPK2 |
Gene ID : | 225638 |
mRNA Refseq : | NM_001037294.1 |
Protein Refseq : | NP_001032371.1 |
MIM : | |
UniProt ID : | Q91ZB0 |
Products Types
◆ Recombinant Protein | ||
ALPK2-486M | Recombinant Mouse ALPK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPK2-492H | Recombinant Human ALPK2 Protein, GST-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionALPK2 is predominantly expressed in cardiac and skeletal muscle tissues, with lower expression levels observed in other tissues.
ALPK2 can potentially be targeted pharmacologically using specific inhibitors or activators to modulate its activity and downstream signaling pathways.
Mutations in ALPK2 can disrupt its kinase activity and alter downstream signaling pathways, leading to pathological conditions.
The mechanisms underlying ALPK2-mediated signal transduction involve complex intracellular signaling cascades, including protein phosphorylation, calcium signaling, and gene expression regulation.
Dysregulation of ALPK2 is associated with various cardiovascular diseases, including cardiomyopathies and arrhythmias, as well as genetic disorders such as familial cardiomyopathy.
ALPK2 is critical for proper cardiac function and cardiovascular development, and its dysregulation can lead to various cardiac disorders.
ALPK2 has several known substrates and downstream effectors involved in calcium handling, sarcomere organization, and signal transduction.
ALPK2 can interact with other proteins, such as ion channels, scaffolding proteins, and signaling molecules, forming protein complexes that modulate its activity and signaling specificity.
ALPK2 is involved in regulating cell cycle progression, apoptosis, and DNA damage response in specific cellular contexts, contributing to cellular homeostasis and disease development.
ALPK2 is implicated in the regulation of calcium homeostasis and ion channel function, particularly in cardiac muscle cells.
Customer Reviews (3)
Write a reviewExcellent crystal quality improvement in crystallization.
Accurate protein biomarker quantification in clinical samples.
Sensitive bioactivity assay performance.
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