Recombinant Mouse AMIGO3 Protein
Cat.No. : | AMIGO3-1600M |
Product Overview : | Recombinant Mouse AMIGO3 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Amigo3 adhesion molecule with Ig like domain 3 [ Mus musculus ] |
Official Symbol : | AMIGO3 |
Gene ID : | 320844 |
mRNA Refseq : | NM_177275.4 |
Protein Refseq : | NP_796249.1 |
MIM : | |
UniProt ID : | Q8C2S7 |
Products Types
◆ Recombinant Protein | ||
AMIGO3-310R | Recombinant Rat AMIGO3 Protein, His (Fc)-Avi-tagged | +Inquiry |
AMIGO3-506M | Recombinant Mouse AMIGO3 Protein, His (Fc)-Avi-tagged | +Inquiry |
AMIGO3-525H | Recombinant Human AMIGO3 protein, GST-tagged | +Inquiry |
AMIGO3-0014H | Recombinant Human AMIGO3 Protein (Thr20-Thr383), C-His-tagged | +Inquiry |
AMIGO3-654R | Recombinant Rat AMIGO3 Protein | +Inquiry |
◆ Lysates | ||
AMIGO3-8881HCL | Recombinant Human AMIGO3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAMIGO3 exhibits a unique tissue-specific expression pattern, with prominent expression in the central nervous system, particularly in regions involved in neuronal development and synaptic transmission, and lower expression in other organs.
Modulation of AMIGO3 expression or activity has the potential to influence neuronal plasticity and regeneration, promoting axonal growth and functional recovery in the context of injury or neurodegenerative conditions.
AMIGO3 may play a role in the formation and maintenance of myelin sheaths in the peripheral nervous system, contributing to proper nerve conduction and insulation of axons.
The regulation of AMIGO3 expression during brain development and in response to environmental stimuli involves complex molecular mechanisms, including transcriptional regulation, epigenetic modifications, and signaling pathways that respond to cues from the local microenvironment.
Different isoforms of AMIGO3 may have distinct functions, potentially influencing cellular processes such as neurite outgrowth, synaptogenesis, and cell adhesion in a context-dependent manner.
Targeting AMIGO3 expression or activity may hold promise as a therapeutic strategy for neurological conditions or neurodegenerative diseases, and further research is needed to understand its precise role and potential therapeutic implications.
Knockout or overexpression studies of AMIGO3 have revealed its critical role in neuronal connectivity and synaptic function, affecting processes such as dendritic arborization, synapse formation, and neurotransmitter release.
AMIGO3 interacts with specific cell adhesion molecules and signaling receptors, including members of the immunoglobulin superfamily and receptor tyrosine kinases, activating downstream signaling pathways involved in axonal guidance, cytoskeletal remodeling, and synaptic plasticity.
AMIGO3 plays a crucial role in neural development and axonal outgrowth, promoting the extension and guidance of growing axons during neuronal circuit formation.
Genetic variations in the AMIGO3 gene have been associated with neurological disorders, cognitive traits, and susceptibility to certain psychiatric conditions, suggesting a role in disease susceptibility and cognitive function.
Customer Reviews (3)
Write a reviewConsistent and reliable results across different experimental conditions.
High-resolution imaging for detailed protein localization.
Precise measurement of protein activity and function.
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