Recombinant Mouse Apba3, His-tagged

• Cat.No.: Apba3-3436M
• Product Overview: Amyloid beta A4 precursor protein-binding family A member 3 (Apba3)

Specification

• Source: E. Coli or Yeast
• Species: Mouse
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 571
• Purity: >90%
• Notes: Small volumes of Apba3 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 [ Mus musculus ]
• Official Symbol: Apba3
• Synonyms: APBA3; amyloid beta (A4) precursor protein-binding, family A, member 3; amyloid beta A4 precursor protein-binding family A member 3; Mint 3; adapter protein X11gamma; neuron-specific X11L2 protein; neuronal munc18-1-interacting protein 3; mint3; Mint-3; lin-10; AW208791; X11gamma
• Gene ID: 57267
• mRNA Refseq: NM_018758
• Protein Refseq: NP_061228
• Function: beta-amyloid binding; enzyme binding

Reviews

07/05/2021

The short half-life and high clearance characteristics of APBA3 allow it to better interact with other drugs, so as to better play the effect of combination therapy.

06/20/2021

Green production process of APBA3 realizes the efficient use of energy, reduces energy consumption, reduces carbon emissions, and is very friendly to the environment.

02/19/2021

APBA3 is highly stable and reproducible, which brings great convenience to our experiments. The results of each experiment are very consistent, giving us more confidence in its quality and reliability.

09/14/2020

Stability of APBA3 is very good, and the results remain consistent after repeated use, showing good product quality.

Q&As

What is the application prospect of APBA3 in neurodegenerative diseases?

The application prospects of APBA3 in neurodegenerative diseases are still uncertain, but its involvement in synaptic transmission and neurotransmitter regulation may have potential value in the treatment of such diseases.

Do APBA3 proteins interact with other proteins?

Yes, the APBA3 protein can interact with other proteins, including those involved in synaptic transmission and neurotransmitter regulation.

What are the potential clinical applications of APBA3 ?

Recombinant APBA3 protein has potential clinical applications, including neurodegenerative diseases, cognitive disorders and cancer treatment.

Does APBA3 have side effects?

The side effects of APBA3 are currently unclear and require further clinical studies and validation.

What are the structural and functional characteristics of APBA3 protein?

APBA3 protein is a multi-domain protein whose main function is to participate in the regulation of signal transduction and synaptic transmission of neurotransmitters.

What is the effect of APBA3 on cognitive function?

Recombinant APBA3 may have a positive effect on cognitive function, improving cognition by regulating synaptic transmission and neurotransmitter balance.

How is the clinical trial of APBA3 progressing?

At present, the clinical trial of APBA3 is under way, and the specific progress needs to consult the relevant clinical research institutions.

What is the mechanism of action of APBA3 in cancer therapy?

The mechanism of action of APBA3 in cancer therapy is not clear, but some studies suggest that it may be involved in the regulation of signal transduction pathways, thereby inhibiting tumor growth and metastasis.

Can APBA3 be administered orally to patients?

Whether the recombinant APBA3 protein can be administered orally to patients still needs further study. At present, it is mainly administered by injection.

How is APBA3 synthesized and purified?

Recombinant APBA3 proteins are usually synthesized in cells by genetic engineering techniques and then purified and purified, for example using affinity chromatography.