Recombinant Mouse Arachidonate 12-lipoxygenase, His-tagged
Cat.No. : | Alox12-584M |
Product Overview : | Recombinant Mouse Alox12 fused with N-terminal his-tagged protein, was expressed using thebaculovirussystem. MW = 76.4 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Alox12-584M |
Description : | 12-Lipoxygenase(12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also produce 15-HpETE, however, platelet-type predominately forms 12-HpETE. Epidermal-type 12(S)- and 12(R)-LO enzymes have also been characterized, which catalyze the synthesis of their respective stereospecific 12-HETE products. |
Source : | Baculovirus. |
Purity : | ≥85%. |
Formulation : | 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol. |
Stability : | ≥6 months at -80°C; avoid freeze/thaw cycles by aliquoting the protein and storing at -80°C. |
Gene Name : | Alox12 arachidonate 12-lipoxygenase [ Mus musculus ] |
Synonyms : | Alox12; arachidonate 12-lipoxygenase; P-12LO; Alox12p; 9930022G08Rik; arachidonate 12-lipoxygenase, 12S-type; 12S-LOX; 12S-lipoxygenase; OTTMUSP00000006289; platelet-type lipoxygenase 12; EC 1.13.11.31 |
Gene ID : | 11684 |
mRNA Refseq : | NM_007440 |
Protein Refseq : | NP_031466 |
UniProt ID : | P39655 |
Chromosome Location : | 11 B3; 11 40.0 cM |
Pathway : | Arachidonic acid metabolism; Metabolic pathways |
Function : | arachidonate 12-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
Products Types
◆ Recombinant Protein | ||
ALOX12-01H | Recombinant Human ALOX12 Protein | +Inquiry |
Alox12-104M | Recombinant Mouse Alox12 Protein, His-tagged | +Inquiry |
Alox12-578M | Recombinant Mouse Alox12 Protein, MYC/DDK-tagged | +Inquiry |
Alox12-021M | Recombinant mouse Alox12 Protein, His-tagged | +Inquiry |
ALOX12-323H | Recombinant Human ALOX12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ALOX12-64HCL | Recombinant Human ALOX12 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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