Recombinant Mouse ASAH1 Protein (19-141 aa), His-GST-Myc-tagged
Cat.No. : | ASAH1-2093M |
Product Overview : | Recombinant Mouse ASAH1 Protein (19-141 aa) is produced by E. coli expression system. This protein is fused with a 10xHis-GST tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Signal Transduction. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. |
Source : | E. coli |
Species : | Mouse |
Tag : | His-GST-Myc |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 43.8 kDa |
Protein length : | 19-141 aa |
AA Sequence : | QAQDVPPWTEDCRKSTYPPSGPTYR GPVPWHTINLDLPPYKRWHELLAQK APALRILVNSITSLVNTFVPSGKLM KMVDQKLPGMIGSLPDPFGEEMRGI ADVTGIPLGEIISFNIFYELFTM |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Asah1 N-acylsphingosine amidohydrolase 1 [ Mus musculus ] |
Official Symbol : | ASAH1 |
Synonyms : | ASAH1; acid ceramidase; ACDase; acid CDase; acylsphingosine deacylase; AC; Asah; 2310081N20Rik; |
Gene ID : | 11886 |
mRNA Refseq : | NM_019734 |
Protein Refseq : | NP_062708 |
UniProt ID : | Q9WV54 |
Products Types
◆ Recombinant Protein | ||
ASAH1-470R | Recombinant Rat ASAH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASAH1-65C | Recombinant Cynomolgus Monkey ASAH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASAH1-524H | Recombinant Human ASAH1 Protein, His-tagged | +Inquiry |
ASAH1-1134H | Recombinant Human ASAH1 Protein, His-SUMO-tagged | +Inquiry |
Asah1-655M | Recombinant Mouse Asah1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ASAH1-8670HCL | Recombinant Human ASAH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (8)
Ask a questionGiven the involvement of ASAH1 in various diseases, including cancer, modulating its activity or developing ASAH1 inhibitors holds promise as potential therapeutic strategies.
Yes, alterations in ASAH1 gene expression or activity can impact cellular differentiation processes, as ceramide metabolism is crucial for normal development and tissue homeostasis.
Yes, mutations or deficiencies in the ASAH1 gene are associated with Farber disease, a rare inherited disorder characterized by the accumulation of ceramide in tissues throughout the body.
ASAH1 deficiency, as seen in Farber disease, is a genetic disorder. Prevention involves genetic counseling for at-risk individuals and prenatal testing during pregnancy.
Currently, ASAH1 deficiency is not included in routine newborn screening panels. However, advancements in testing methods may lead to its inclusion in the future.
Besides its role in ceramide metabolism, the ASAH1 protein can affect immune response, inflammation, and cellular stress responses.
Dysfunction of the ASAH1 protein impairs the breakdown of ceramide, leading to its accumulation in various tissues and disrupting cellular homeostasis.
Yes, the ASAH1 protein can modulate signaling pathways like the sphingosine-1-phosphate pathway, which influences various cellular processes such as migration, inflammation, and angiogenesis.
Customer Reviews (3)
Write a reviewSuch dedicated support makes me feel confident in my choice of using the ASAH1 protein for my experiments.
The manufacturer's commitment to excellence is truly commendable, especially when it comes to their outstanding technical support.
The ASAH1 Protein is a protein of exceptional quality that surpasses my expectations and fulfills all my experimental requirements.
Ask a Question for All ASAH1 Products
Required fields are marked with *
My Review for All ASAH1 Products
Required fields are marked with *
Inquiry Basket