Recombinant Mouse Asb6 Protein, Myc/DDK-tagged

• Cat.No.: Asb6-1735M
• Product Overview: Purified recombinant protein of mouse full-length ankyrin repeat and SOCS box-containing 6 (Asb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 46.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Asb6 ankyrin repeat and SOCS box-containing 6 [ Mus musculus (house mouse) ]
• Official Symbol: Asb6
• Synonyms: ASB6; ankyrin repeat and SOCS box-containing 6; ankyrin repeat and SOCS box protein 6; ASB-6; ankyrin repeat and SOCS box-containing protein 6; AA409356; 2510004M11Rik
• Gene ID: 72323
• mRNA Refseq: NM_133346
• Protein Refseq: NP_579924
• UniProt ID: Q91ZU1

Reviews

04/08/2021

Its high specificity and robust activity make it an ideal candidate for investigating intricate molecular interactions and elucidating complex biological mechanisms.

07/08/2019

This variety allows me to select the most appropriate option based on the specific requirements of my research.

07/17/2018

With its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.

Q&As

Are there any known molecular interactions involving ASB6?

The molecular interactions involving ASB6 are not well-characterized. Identifying its binding partners or protein substrates would provide insights into its functional mechanisms.

Are there any known upstream regulators that can modulate ASB6 expression?

The specific upstream regulators that modulate ASB6 expression have not been extensively investigated. Further studies are needed to identify the regulatory mechanisms involved.

Can ASB6 be used as a diagnostic marker for any diseases or conditions?

Currently, ASB6 has not been identified as a diagnostic marker for any specific diseases or conditions. Further investigations may reveal its potential diagnostic applicability.

Is there any evidence to suggest a role for ASB6 in cancer development?

There is limited research on the role of ASB6 in cancer development. While some studies have suggested a possible involvement of ASB6 in certain types of cancer, additional research is required to establish a definitive link.