Recombinant Mouse Cfl2 Protein, MYC/DDK-tagged

• Cat.No.: Cfl2-881M
• Product Overview: Purified recombinant protein of full-length mouse cofilin 2, muscle (Cfl2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Broad expression in heart adult (RPKM 32.0), bladder adult (RPKM 27.8) and 24 other tissues
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 18.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cfl2 cofilin 2, muscle [ Mus musculus (house mouse) ]
• Official Symbol: Cfl2
• Synonyms: Cfl2; cofilin 2, muscle; cofilin-2; cofilin, muscle isoform
• Gene ID: 12632
• mRNA Refseq: NM_007688
• Protein Refseq: NP_031714
• UniProt ID: P45591

Reviews

05/23/2022

It has been extensively used in protein-protein interaction studies, enzymatic assays, and structural analyses, showcasing its reliability and adaptability in diverse research areas.

11/13/2021

I am certain of obtaining reliable and reproducible results, enabling me to contribute to scientific progress and make new discoveries.

11/07/2017

I highly recommend the CFL2 Protein for its outstanding performance in ELISA assays.

Q&As

Are there any ongoing clinical trials targeting CFL2 for therapeutic purposes?

It's important to check current clinical trial databases for the latest information, but research exploring CFL2 as a therapeutic target is ongoing.

How does CFL2 relate to cardiac diseases?

CFL2 is involved in maintaining the structure and function of cardiac muscle cells, and its dysregulation has been linked to conditions such as cardiomyopathies.

Are there diagnostic applications for CFL2 in muscle-related disorders?

Research suggests that analyzing CFL2 levels and activity could serve as diagnostic markers for certain muscle-related disorders.

How does CFL2 interact with other proteins in the context of muscle function?

CFL2 interacts with actin and other regulatory proteins to modulate the dynamics of the actin cytoskeleton, influencing cellular processes crucial for muscle function.

Can CFL2 be a potential therapeutic target for muscle-related disorders?

Investigating CFL2 as a therapeutic target is an active area of research, with the aim of developing interventions for conditions characterized by impaired muscle function.