Recombinant Mouse Chac1 Protein, Myc/DDK-tagged
Cat.No. : | Chac1-2134M |
Product Overview : | Purified recombinant protein of mouse full-length ChaC, cation transport regulator 1 (Chac1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 24.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Chac1 ChaC, cation transport regulator 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Chac1 |
Synonyms : | Chac1; ChaC, cation transport regulator 1; Botc; 1810008K03Rik; glutathione-specific gamma-glutamylcyclotransferase 1; ChaC, cation transport regulator-like 1; blocks Notch protein; botch; cation transport regulator-like protein 1; gamma-GCG 1; EC 4.3.2.7 |
Gene ID : | 69065 |
mRNA Refseq : | NM_026929 |
Protein Refseq : | NP_081205 |
UniProt ID : | Q8R3J5 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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