Recombinant Mouse COL4A2 Protein (1481-1707 aa), His-sumostar-tagged
Cat.No. : | COL4A2-2327M |
Product Overview : | Recombinant Mouse COL4A2 Protein (1481-1707 aa) is produced by Yeast expression system. This protein is fused with a 6xHis-sumostar tag at the N-terminal. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. |
Source : | Yeast |
Species : | Mouse |
Tag : | His-sumostar |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 41.1 kDa |
Protein length : | 1481-1707 aa |
AA Sequence : | VSIGYLLVKHSQTDQEPMCPVGMNK LWSGYSLLYFEGQEKAHNQDLGLAG SCLARFSTMPFLYCNPGDVCYYASR NDKSYWLSTTAPLPMMPVAEEEIKP YISRCSVCEAPAVAIAVHSQDTSIP HCPAGWRSLWIGYSFLMHTAAGDEG GGQSLVSPGSCLEDFRATPFIECNG GRGTCHYFANKYSFWLTTIPEQNFQ STPSADTLKAGLIRTHISRCQVCMK NL |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | Col4a2 collagen, type IV, alpha 2 [ Mus musculus ] |
Official Symbol : | COL4A2 |
Synonyms : | COL4A2; collagen, type IV, alpha 2; collagen alpha-2(IV) chain; canstatin; Col4a-2; MGC7371; |
Gene ID : | 12827 |
mRNA Refseq : | NM_009932 |
Protein Refseq : | NP_034062 |
UniProt ID : | P08122 |
Products Types
◆ Recombinant Protein | ||
COL4A2-335H | Recombinant Human COL4A2 Protein, His-tagged | +Inquiry |
COL4A2-2373M | Recombinant Mouse COL4A2 Protein (1481-1707 aa), His-tagged | +Inquiry |
COL4A2-1263H | Recombinant Human COL4A2 protein, His-tagged | +Inquiry |
COL4A2-1765H | Recombinant Human COL4A2 Protein (Gly1441-Ala1669), N-His tagged | +Inquiry |
COL4A2-2714H | Recombinant Human COL4A2 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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