Active Recombinant Mouse F2 protein(Met1-Gly618), His-tagged
Cat.No. : | F2-1186M |
Product Overview : | Recombinant Mouse F2 protein(NP_034298.1)(Met1-Gly618), fused with C-terminal His tag, was expressed in HEK293. |
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similar : | F2 |
Alias : | F2; coagulation factor II; prothrombin; Cf2; FII; Cf-2; thrombin; |
Source : | HEK293 |
Species : | Mouse |
Conjugate : | C-His |
Tag : | C-His |
Protein length : | Met1-Gly618 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
MolecularMass : | The secreted recombinant mouse F2 consists of 605 amino acids (pro form) and has a calculated molecular mass of 69.3 kDa. The apparent molecular mass of the recombinant mouse F2 is approximately 85 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 96 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : | F2 coagulation factor II [ Mus musculus ] |
GeneNameWeblink : | 14061 |
OfficialSymbol : | F2 |
OfficialSymbolWeblink : | 14061 |
GeneID : | 14061 |
GeneIDWeblink : | 14061 |
mRNARefseq : | NM_010168 |
mRNARefseqWeblink : | NM_010168.2 |
ProteinRefseqWeblink : | NP_034298.1 |
Synonyms : | F2; coagulation factor II; prothrombin; Cf2; FII; Cf-2; thrombin; |
Synonyms : | F2; coagulation factor II; prothrombin; Cf2; FII; Cf-2; thrombin; |
Products Types
◆ Recombinant Protein | ||
F2-366R | Recombinant Rat F2 Protein, His-tagged | +Inquiry |
F2-995M | Recombinant Mouse F2 Protein, MYC/DDK-tagged | +Inquiry |
F2-3610H | Recombinant Human F2 Protein, GST-tagged | +Inquiry |
F2-882H | Recombinant Human F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
F2-1356R | Recombinant Rhesus Macaque F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
Prothrombin-59H | Native Human Prothrombin Frag 1 | +Inquiry |
Thrombin-61M | Active Native Mouse Thrombin | +Inquiry |
Prothrombin-270B | Active Native Bovine Prothrombin | +Inquiry |
◆ Lysates | ||
F2-2124MCL | Recombinant Mouse F2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe F2 gene plays a crucial role in the synthesis of vitamin K-dependent clotting factors, including prothrombin. Disruptions in this process, often due to genetic or nutritional factors, can contribute to coagulation disorders, impacting hemostasis and blood clotting.
Transcriptional regulation of the F2 gene involves factors like vitamin K-dependent gamma-carboxylation. Hepatocytes synthesize prothrombin under the influence of vitamin K and other coagulation factors.
The F2 gene encodes prothrombin, a crucial factor in blood coagulation. Prothrombin is converted to thrombin, a key enzyme in the clotting cascade, facilitating fibrin formation.
Genetic variations in F2, including polymorphisms, can influence prothrombin function. Certain variants may predispose individuals to thrombotic or bleeding disorders.
Genetic variations in the F2 gene can influence prothrombin levels, affecting an individual's propensity for thrombotic events. Certain variants may predispose individuals to a higher or lower risk of abnormal blood clot formation.
Customer Reviews (3)
Write a reviewQuality control is evident. This product ensures accuracy in our studies.
Our lab swears by this protein. Fast shipping is a definite bonus.
Consistently reliable. The shipping speed is appreciated in our fast-paced lab.
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