Recombinant Mouse IL-1 alpha
Cat.No. : | IL1a-92M |
Product Overview : | Mouse IL-1 alpha was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
- Specification
- Gene Information
- Related Products
Description : | The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an "alarmin" released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation. |
Source : | Yeast |
Species : | Mouse |
Form : | Lyophilized |
Molecular Mass : | 18.0 kDa |
AA Sequence : | SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS (156) |
Applications : | The Mouse IL-1 alpha protein can be used in cell culture, as an IL-1 alpha ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | Il1a interleukin 1 alpha [ Mus musculus ] |
Official Symbol : | IL1a |
Synonyms : | IL1A; interleukin 1 alpha; interleukin-1 alpha; IL-1 alpha; Il-1a; |
Gene ID : | 16175 |
mRNA Refseq : | NM_010554 |
Protein Refseq : | NP_034684 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; |
Function : | copper ion binding; cytokine activity; interleukin-1 receptor binding; |
Products Types
◆ Recombinant Protein | ||
Il1a-097M | Active Recombinant Mouse Il1a Protein | +Inquiry |
IL1A-148H | Active Recombinant Human IL1A Protein | +Inquiry |
IL1A-2687R | Recombinant Rat IL1A Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1A-159H | Recombinant Active Human IL1A Protein, His-tagged(C-ter) | +Inquiry |
IL1A-160P | Recombinant Active Pig IL1A Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL1A-2911HCL | Recombinant Human IL1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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