Recombinant Mouse Il12a Protein (Met1-Ala215), C-His and C-TwinStrep tagged
Cat.No. : | Il12a-6738M |
Product Overview : | Recombinant mouse Il12a (Met1-Ala215) fused with the C-terminal His Tag and mouse Il12b (Met1-Ser335) fused with the C-terminal Twin-Strep tag was expressed in mammalian cells. |
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Description : | Enables interleukin-12 beta subunit binding activity. Contributes to cytokine activity. Acts upstream of or within several processes, including T-helper 1 cell activation; defense response to protozoan; and positive regulation of T cell activation. Located in cell surface; cytoplasm; and extracellular space. Part of interleukin-12 complex. Is expressed in brain; lung; small intestine; testis; and thymus. Human ortholog (s) of this gene implicated in hepatitis C; hepatocellular carcinoma; and primary biliary cholangitis. Orthologous to human IL12A (interleukin 12A). |
Source : | Mammalian cells |
Species : | Mouse |
Tag : | C-His and C-TwinStrep |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 66.4 kDa (25.2+41.2) |
Protein Length : | Met1-Ala215 |
Purity : | > 90 % as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | Il12a interleukin 12a [ Mus musculus (house mouse) ] |
Official Symbol : | Il12a |
Synonyms : | Il12a; interleukin 12a; p35; Ll12a; Il-12a; IL-12p35; interleukin-12 subunit alpha; CLMF p35; IL-12 p35 subunit; IL-12 subunit p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12a p35 subunit; interleukin-12 p35 subunit |
Gene ID : | 16159 |
mRNA Refseq : | NM_001159424 |
Protein Refseq : | NP_001152896 |
UniProt ID : | P43431 |
Products Types
◆ Recombinant Protein | ||
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IL12A-176H | Active Recombinant Human IL12A Protein (Arg23-Ser219), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Il12a-47M | Active Recombinant Mouse Il12a Protein (Arg23-Ala215), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL12A-4327HG | Active Recombinant Human IL12A protein | +Inquiry |
IL12A-062H | Active Recombinant Human IL12 Protein | +Inquiry |
◆ Lysates | ||
IL12A-2435HCL | Recombinant Human IL12A cell lysate | +Inquiry |
IL12A-001CCL | Recombinant Cynomolgus IL12A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionMass spectrometry identifies IL12A's post-translational modifications and their roles.
Knockout models validate IL12A's roles in immune response modulation.
Protein footprinting assays reveal IL12A's binding interfaces with receptors.
ELISA and stability assays quantify IL12A secretion and stability in culture.
SPR characterizes IL12A's interactions with antibodies and inhibitors.
Cellular assays gauge IL12A's cytokine induction in immune cells.
Isothermal titration calorimetry measures IL12A's binding affinity with receptors.
Structural biology techniques analyze IL12A genetic variant impacts.
Site-directed mutagenesis probes IL12A's functional domains and interactions.
Bioluminescence imaging tracks IL12A expression dynamics in vivo.
Customer Reviews (3)
Write a reviewSuitable for co-immunoprecipitation.
Consistent in bioactivity.
Good for receptor binding studies.
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