Recombinant Mouse Il1rl1 Protein (Ser27-Ala337), C-Fc tagged

• Cat.No.: Il1rl1-5714M
• Product Overview: Recombinant mouse IL1RL1 (Ser27-Ala337) fused with the C-terminal Fc tag was expressed in mammalian cells.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: C-Fc
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 59.21 kDa
• Protein Length: Ser27-Ala337
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Il1rl1 interleukin 1 receptor-like 1 [ Mus musculus (house mouse) ]
• Official Symbol: Il1rl1
• Synonyms: IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; T1; protein T1; lymphocyte antigen 84; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
• Gene ID: 17082
• mRNA Refseq: NM_001025602
• Protein Refseq: NP_001020773
• UniProt ID: P14719

Reviews

07/25/2019

High specificity in ELISA.

01/30/2017

Suitable for flow cytometry.

07/13/2016

Effective in allergy models.

Q&As

Are there any splice variants of IL1RL1?

IL1RL1 has multiple splice variants that differ in signaling capabilities.

What is the role of IL1RL1 in allergic responses?

IL1RL1 suppresses allergic responses by inhibiting mast cell activation.

Does IL1RL1 have a role in autoimmune diseases?

IL1RL1 is implicated in rheumatoid arthritis.

How does IL1RL1 affect cytokine production?

IL1RL1 increases the production of IL-4 and IL-13.

What is the subcellular localization of IL1RL1?

IL1RL1 is primarily membrane-bound.

Does IL1RL1 influence T-cell differentiation?

IL1RL1 promotes Th2 cell differentiation.

How does IL1RL1 interact with its ligands?

IL1RL1 binds to IL-33 and IL-36 to initiate signaling.

Is IL1RL1 expression altered in any cancers?

IL1RL1 expression is altered in lung and breast cancer.

What post-translational modifications occur on IL1RL1?

IL1RL1 undergoes glycosylation and phosphorylation.

How is IL1RL1 expression regulated in asthmatic conditions?

IL1RL1 expression is upregulated in asthmatic conditions.