Recombinant Mouse IL1RL2 Protein (22-338 aa), His-tagged

• Cat.No.: IL1RL2-1983M
• Product Overview: Recombinant Mouse IL1RL2 Protein (22-338 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Immunology. Protein Description: Partial.

Specification

• Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 40.0 kDa
• Protein length: 22-338 aa
• AA Sequence: DTCEDIFMHNVIISEGQPFPFNCTY PPETNGAVNLTWYKTPSKSPVSNNR HLRVHQDQTWILFLPLTLEDSGIYQ CVIRNAHNCYQIAVNLTVLKNHWCD SSMEGSPVNSPDVYQQILPIGKSGS LNCHLYFPESCALDSIKWYKGCEEI KAGKKYSPSGAKLLVNNVAVEDGGS YACSARLTHLGRHFTIRNYIAVNTK EVEYGRRIPNITYPKNNSIEVPLGS TLIVNCNITDTKENTNLRCWRVNNT LVDDYYKDSKRIQEGIETNVSLRDQ IRYTVNITFLKVKMEDYGRPFTCHA GVSAAYIILIYPVPDFR
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: Il1rl2 interleukin 1 receptor-like 2 [ Mus musculus ]
• Official Symbol: IL1RL2
• Synonyms: IL1RL2; IL1R-rp2; AI481289; AW551444; IL-1Rrp2
• Gene ID: 107527
• mRNA Refseq: NM_133193
• Protein Refseq: NP_573456
• UniProt ID: Q9ERS7