Recombinant Mouse Il33 Protein

• Cat.No.: Il33-3521M
• Product Overview: Purified recombinant protein of Mouse interleukin 33 (Il33), transcript variant 2 without tag was expressed in E. coli.

Specification

• Description: In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.
• Source: E. coli
• Species: Mouse
• Molecular Mass: 17.6 kDa
• Protein length: Ser109-Ile266
• Endotoxin: Less than 0.1 EU/μg (<0.01 ng/μg) protein as determined by the LAL method
• Purity: > 98%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 20 mM HEPES, 150 mM NaCl, pH 7.2, 10 mM TCEP

Gene Information

• Gene Name: Il33 interleukin 33 [ Mus musculus (house mouse) ]
• Official Symbol: Il33
• Synonyms: Il33; interleukin 33; Il-; Il1f; NF-H; Il-33; Il1f11; NF-HEV; 9230117N10Rik; interleukin-33; nuclear factor from high endothelial venules
• Gene ID: 77125
• mRNA Refseq: NM_133775
• Protein Refseq: NP_598536
• UniProt ID: Q8BVZ5